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KIF11 / EG5

kinesin family member 11

Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.

Gene Name: kinesin family member 11
Synonyms: KIF11, EG5, Kinesin family member 11, Kinesin-like protein 1, Kinesin-like 1, Kinesin-like protein KIF11, MCLMR, TRIP5, HKSP, KNSL1, TR-interacting protein 5, TRIP-5
Target Sequences: NM_004523 NP_004514.2 P52732

Publications (5)

1
Prophase microtubule arrays undergo flux-like behavior in mammalian cells. Ferenz NP, Wadsworth P. Molecular biology of the cell. 2007 18:3993-4002. [PubMed:17671163] [PMC:PMC1995704]
2
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis. Xu G, Watanabe T, Iso Y, Koba S, Sakai T, Nagashima M, Arita S, Hongo S, Ota H, Kobayashi Y, Miyazaki A, Hirano T. Circulation research. 2009 105:500-10. [PubMed:19644050]
3
Kinesin molecular motor Eg5 functions during polypeptide synthesis. Bartoli KM, Jakovljevic J, Woolford JL, Saunders WS. Molecular biology of the cell. 2011 22:3420-30. [PubMed:21795388] [PMC:PMC3172266] Related Antibodies: LS-C40939.
4
Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2. Gable A, Qiu M, Titus J, Balchand S, Ferenz NP, Ma N, Collins ES, Fagerstrom C, Ross JL, Yang G, Wadsworth P. Molecular biology of the cell. 2012 23:1254-66. (ICC, WB; Pig) [PubMed:22337772] [PMC:PMC3315814]
5
Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Lawo S, Hasegan M, Gupta GD, Pelletier L. Nature cell biology. 2012 14:1148-58. (WB; Human) [PubMed:23086237]
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KIF11 / EG5 ELISA Kit
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Cell-Based Phosphorylation
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Colorimetric - 450nm (TMB)
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KIF11 / EG5 ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).