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KIAA1524 / p90 Autoantigen

KIAA1524

Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.

Gene Name: KIAA1524
Synonyms: KIAA1524, Cancerous inhibitor of PP2A, CIP2A, Protein CIP2A, p90 autoantigen, p90
Target Sequences: AB040957 BAA96048.1 Q8TCG1

Publications (4)

1
CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells. Li W, Ge Z, Liu C, Liu Z, Bjrkholm M, Jia J, Xu D. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008 14:3722-8. (IHC, WB; Human) [PubMed:18559589]
2
CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation. Wang J, Li W, Li L, Yu X, Jia J, Chen C. International journal of laboratory hematology. 2011 33:290-8. (WB; Human) [PubMed:21219591]
3
CIP2A expression is associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis. Lee J, Park EJ, Hwang JW, Oh JM, Kim H, Bae EK, Choi YL, Han J, Ahn JK, Cha HS, Koh EM. Rheumatology international. 2012 32:2023-30. (IHC, WB; Human) [PubMed:21479604]
4
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer. Ma L, Wen ZS, Liu Z, Hu Z, Ma J, Chen XQ, Liu YQ, Pu JX, Xiao WL, Sun HD, Zhou GB. PloS one. 2011 6:e20159. (IHC, WB; Human) [PubMed:21655278] [PMC:PMC3105001]
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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
KIAA1524 / p90 Autoantigen (4)
No (4)
His-GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
KIAA1524 / p90 Autoantigen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
102 kDa
20 µg/$215
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HEK 293 Cells
Myc-DDK (Flag)
102 kDa
20 µg/$1,107
KIAA1524 / p90 Autoantigen Protein - Recombinant  Cancerous Inhibitor Of PP2A By SDS-PAGE
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E. coli
His-GST
69.2 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,601
KIAA1524 / p90 Autoantigen Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
102 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).