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KIAA0430

Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks.

Gene Name: KIAA0430
Synonyms: KIAA0430, Limkain b1, Limkain-b1, LKAP, MARF1, PPP1R34
Target Sequences: AA714835 BAA24860.3 Q9Y4F3

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Antibodies (2)
Primary (2)
KIAA0430 (2)
Human (2)
Mouse (1)
WB (1)
IP (1)
rabbit (2)
IgG (2)
polyclonal pc (2)
Unconjugated (2)
aa1625-1675 (1)
No (2)
KIAA0430 Antibody - Detection of Human and Mouse Limkain b1 by Western Blot. Samples: Whole cell lysate from Jurkat (15 and 50 ug), HeLa (50 ug), 293T (50 ug), and mouse NIH3T3 (50 ug) cells. Antibodies: Affinity purified rabbit anti-Limkain b1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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KIAA0430 Rabbit anti-Human Polyclonal (aa1625-1675) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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KIAA0430 Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$351
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).