KIAA0191 / ZCCHC11

zinc finger, CCHC domain containing 11

Uridylyltransferase that acts as a suppressor of microRNA (miRNA) biogenesis by specifically mediating the terminal uridylation of some miRNAs. Catalyzes the 3' uridylation of precursor let-7 (pre-let-7), a miRNA precursor. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cells and is required for ES cells to maintain pluripotency. Does not bind RNA by itself, recruited to pre-let-7 miRNAs via its interaction with LIN28A and LIN28B. Also catalyzes the 3' uridylation of miR-26A, a miRNA that represses IL6 transcript, leading to abrogate IL6 transcript repression and promote cytokine expression. May also suppress Toll-like receptor-induced NF-kappa-B activity via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation.

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Products

Antibodies (16)

Type

Primary (16)

Target

KIAA0191 / ZCCHC11 (16)

Reactivity

Human (14)

Mouse (7)

Rat (2)

Bat (4)

Bovine (4)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Hamster (2)

Horse (1)

Monkey (1)

Pig (4)

Rabbit (1)

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Application

IHC (7)

IHC-P (7)

WB (14)

ELISA (3)

IF (3)

IP (2)

Peptide-ELISA (3)

Host

rabbit (14)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (7)

Clonality

polyclonal pc (16)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (13)

Epitope

aa1403-1452 (4)

aa250-300 (2)

aa1-50 (1)

aa1568-1600 (1)

aa1631-1644 (1)

aa830-844 (1)

Publications

No (16)

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KIAA0191 / ZCCHC11 Antibody (aa830-844) LS-C154880

Antibody:

KIAA0191 / ZCCHC11 Goat anti-Mouse Polyclonal (aa830-844) Antibody

Reactivity:

Mouse, Rat, Hamster

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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KIAA0191 / ZCCHC11 Antibody LS-C802690

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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KIAA0191 / ZCCHC11 Antibody (aa1631-1644) LS-C55702

Antibody:

KIAA0191 / ZCCHC11 Goat anti-Human Polyclonal (aa1631-1644) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey

Applications:

IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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KIAA0191 / ZCCHC11 Antibody (aa1403-1452) LS-B8244

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa1403-1452) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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KIAA0191 / ZCCHC11 Antibody (aa1403-1452, HRP) LS-C465404

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa1403-1452) (HRP) Antibody

Reactivity:

Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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KIAA0191 / ZCCHC11 Antibody (aa1403-1452, Biotin) LS-C465402

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa1403-1452) (Biotin) Antibody

Reactivity:

Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

KIAA0191 / ZCCHC11 Antibody (aa1403-1452, FITC) LS-C465403

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa1403-1452) (FITC) Antibody

Reactivity:

Dog, Guinea pig, Bovine, Pig, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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KIAA0191 / ZCCHC11 Antibody LS-C754701

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

KIAA0191 / ZCCHC11 Antibody LS-C754704

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

KIAA0191 / ZCCHC11 Antibody (aa250-300) LS-C289359

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa250-300) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

KIAA0191 / ZCCHC11 Antibody LS-C779024

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

KIAA0191 / ZCCHC11 Antibody (aa250-300) LS-C286934

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa250-300) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

KIAA0191 / ZCCHC11 Antibody (aa1568-1600) LS-C344648

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Mouse Polyclonal (aa1568-1600) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

KIAA0191 / ZCCHC11 Antibody (aa1-50) LS-C286131

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

KIAA0191 / ZCCHC11 Antibody LS-C668196

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

KIAA0191 / ZCCHC11 Antibody LS-C335618

Antibody:

KIAA0191 / ZCCHC11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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