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Kexin / KEX2 is a prohormone processing protease found in the budding yeast (S. cerevisiae). It catalyses the cleavage of -Lys-Arg- and -Arg-Arg- bonds to process yeast alpha-factor pheromone and killer toxin precursors. It shares structural similarities with the bacterial protease subtilisin. The first mammalian homologue of this protein to be identified was furin.
Gene Name: | Kexin KEX2 |
Synonyms: | KEX2 |
Target Sequences: | NP_014161.1 |
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