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KDM5D / JARID1D
lysine (K)-specific demethylase 5D
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.
| Gene Name: | lysine (K)-specific demethylase 5D |
| Synonyms: | KDM5D, H-Y, HYA, HY, JARID1D, Histocompatibility Y antigen, Histone demethylase JARID1D, KIAA0234, Protein SmcY, SMCY, Smcy homolog, Y-linked (mouse), Smcy homolog, Y-linked, Lysine-specific demethylase 5D, SMC homolog, Y chromosome |
| Target Sequences: | NM_004653 NP_004644.2 Q9BY66 |
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