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KDM4C / JMJD2C

lysine (K)-specific demethylase 4C

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Gene Name: lysine (K)-specific demethylase 4C
Synonyms: KDM4C, BA146B14.1, GASC-1 protein, GASC1, Jumonji domain containing 2C, JMJD2C, JHDM3C, KIAA0780, Lysine-specific demethylase 4C
Target Sequences: AB037901 BAB16102.1 Q9H3R0

Publications (2)

1
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Luo W, Chang R, Zhong J, Pandey A, Semenza GL. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:E3367-76. (ChrIP; Human) [PubMed:23129632] [PMC:PMC3523832]
2
iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma. Jin Wook Hwang, Christophe Desterke, Olivier Féraud, Stephane Richard, Sophie Ferlicot, Virginie Verkarre, Jean Jacques Patard, Julien Loisel-Duwattez, Adlen Foudi, Frank Griscelli, Annelise Bennaceur-Griscelli, Ali G Turhan. International journal of molecular sciences. 2019 September;20: [Full Text Article] [PubMed:31575031] [PMC:PMC6801716] Related Antibodies: LS-C114684.

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Products
Antibodies (35)
Primary (35)
KDM4C / JMJD2C (35)
Human (34)
Mouse (6)
Rat (4)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Rabbit (3)
IHC (13)
IHC-P (10)
WB (29)
Flo (8)
ELISA (11)
ICC (1)
IF (5)
IP (1)
Peptide-ELISA (1)
rabbit (29)
mouse (6)
Product Group
IHCPlus (3)
IgG (18)
IgG1 (6)
monoclonal mc (6)
polyclonal pc (29)
OTI4B1 (2)
OTI5B9 (2)
OTI8A1 (2)
APC (1)
APC Conjugated (2)
Biotin Conjugated (4)
Carrier-free (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (17)
aa685-871 (8)
aa1023-1056 (7)
C-Terminus (4)
aa450-600 (2)
aa475-525 (2)
aa350-570 (1)
No (34)
Yes (1)
KDM4C / JMJD2C Antibody - Anti-JMJD2C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KDM4C / JMJD2C Antibody - Anti-JMJD2C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KDM4C / JMJD2C Antibody - Anti-JMJD2C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KDM4C / JMJD2C Antibody - Anti-JMJD2C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
KDM4C / JMJD2C Antibody - IHC of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (OTI4B1) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
100 µl/$434
KDM4C / JMJD2C Antibody - IHC of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (Carrier-free) (OTI4B1) Antibody
Human
Flo, IF, IHC
Unconjugated, Carrier-free
100 µg/$511
KDM4C / JMJD2C Antibody - Anti-JMJD2C antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa450-600) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
KDM4C / JMJD2C Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (OTI5B9) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
KDM4C / JMJD2C Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (Carrier-free) (OTI5B9) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa475-525) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
KDM4C / JMJD2C Antibody - Western blot analysis of extracts of HL-60 cells.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa350-570) Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KDM4C / JMJD2C Antibody - IHC of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (OTI8A1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
KDM4C / JMJD2C Antibody - IHC of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (Dilution 1:50).
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KDM4C / JMJD2C Mouse anti-Human Monoclonal (Carrier-free) (OTI8A1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
KDM4C / JMJD2C Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution of 1:100
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa450-600) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
KDM4C / JMJD2C Antibody - JMJD2C Antibody western blot of K562 cell line lysates (35 ug/lane). The JMJD2C antibody detected the JMJD2C protein (arrow).
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa1023-1056) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
KDM4C / JMJD2C Antibody - Western blot analysis of Mouse heart and brain tissue, using KDM4C Polyclonal Antibody at dilution of 1:800.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KDM4C / JMJD2C Antibody - Western blot of recombinant KDM4C / JMJD2C.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM4C / JMJD2C Rabbit anti-Human Polyclonal (aa685-871) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).