KDM3A / JMJD1A

lysine (K)-specific demethylase 3A

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

KDM3A / JMJD1A (6)

Publications

No (6)

Tag

Myc-DDK (Flag) (6)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (4)

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Human KDM3A / JMJD1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82088

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

20 µg/$215

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Human KDM3A / JMJD1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82087

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

20 µg/$215

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KDM3A / JMJD1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101572

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

100 µg/$710

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KDM3A / JMJD1A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128840

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

100 µg/$710

Select

Human KDM3A / JMJD1A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68395

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

20 µg/$1,107

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Human KDM3A / JMJD1A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68399

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

147.2 kDa

Price:

20 µg/$1,107

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