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KDELR3

KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified, and it encodes a protein highly homologous to KDELR1 and KDELR2 proteins. Two transcript variants of KDELR3 that arise by alternative splicing, and encode different isoforms of KDELR3 receptor, have been described.

Gene Name: KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3
Synonyms: KDELR3
Target Sequences: NM_016657 NP_057839.1 O43731

☰ Filters
Antibodies (9)
Proteins (5)
Over-Expression Lysate (4)
Primary (9)
Recombinant (1)
KDELR3 (14)
Human (9)
Mouse (5)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (2)
IHC-P (1)
WB (9)
ELISA (1)
IF (1)
Peptide-ELISA (2)
rabbit (9)
IgG (3)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
aa71-120 (4)
30-110 aa, Internal (1)
Leu95 (1)
aa61-110 (1)
No (14)
GST (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
KDELR3 Antibody - Western blot of KDEL Receptor 3 antibody
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KDELR3 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KDELR3 Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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KDELR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KDELR3 Antibody - IHC of KDEL Receptor 3 (L95) pAb in paraffin-embedded human brain tissue.
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KDELR3 Rabbit anti-Human Polyclonal (Leu95) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
KDELR3 Antibody - Western blot analysis of lysates from NIH/3T3 cells, using ERD23 Antibody. The lane on the right is blocked with the synthesized peptide.
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KDELR3 Rabbit anti-Human Polyclonal (aa61-110) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
KDELR3 Antibody - KDELR3 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR3 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
KDELR3 Antibody - KDELR3 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR3 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
KDELR3 Antibody - KDELR3 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDELR3 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
KDELR3 Antibody - KDELR3 antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDELR3 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
KDELR3 Antibody - Western blot of NIH-3T3 cell lysate using ERD23 Antibody
Select
KDELR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
KDELR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.8 kDa
20 µg/$150
KDELR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.5 kDa
20 µg/$150
KDELR3 Protein - 12.5% SDS-PAGE of human KDELR3 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.28 kDa
10 µg/$479; 25 µg/$670
KDELR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.8 kDa
100 µg/$494
KDELR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.5 kDa
100 µg/$494
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).