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KCNN1

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.

Gene Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Family/Subfamily: Ion Channel , Potassium channel - calcium-activated
Synonyms: KCNN1, SK1, SKCa 1, Hsk1, KCa2.1, SK, SKCA1
Target Sequences: NM_002248 NP_002239.2 Q92952

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Antibodies (17)
Primary (17)
KCNN1 (17)
Human (17)
Mouse (4)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Monkey (3)
IHC (5)
IHC-P (4)
WB (16)
ELISA (9)
IF (1)
Peptide-ELISA (1)
rabbit (17)
Product Group
IHCPlus (1)
IgG (15)
polyclonal pc (17)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (9)
aa391-419 (7)
aa441-490 (4)
No (17)
KCNN1 Antibody - Western blot analysis of KCNN1 expression in Jurkat cells lysate. The lane on the left is treated with the antigen-specific peptide.
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KCNN1 Antibody - Anti-KCNN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN1 Rabbit anti-Human Polyclonal (aa441-490) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
KCNN1 Antibody - Anti-KCNN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN1 Rabbit anti-Human Polyclonal (aa441-490) (HRP) Antibody
Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
KCNN1 Antibody - Anti-KCNN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN1 Rabbit anti-Human Polyclonal (aa441-490) (Biotin) Antibody
Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
KCNN1 Antibody - Anti-KCNN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KCNN1 Rabbit anti-Human Polyclonal (aa441-490) (FITC) Antibody
Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
KCNN1 Antibody - KCNN1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The KCNN1 antibody detected the KCNN1 protein (arrow).
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) Antibody
Human
WB
Unconjugated
400 µl/$393
KCNN1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using KCNN1 Polyclonal Antibody at dilution of 1:55(×200)
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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KCNN1 Rabbit anti-Human Polyclonal (aa391-419) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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KCNN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).