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KCNK9 / TASK3
potassium channel, subfamily K, member 9
KCNK9 / TASK3 is a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
| Gene Name: | potassium channel, subfamily K, member 9 |
| Family/Subfamily: | Ion Channel , Potassium channel - two pore |
| Synonyms: | KCNK9, KT3.2, K2p9.1, Potassium channel TASK3, TASK3, Two pore K(+) channel KT3.2, TASK-3 |
| Target Sequences: | NM_016601 NP_057685.1 Q9NPC2 |
Publications (1)
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