KCNJ3 / GIRK1

potassium inwardly-rectifying channel, subfamily J, member 3

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.

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Products

Antibodies (44)

ELISA Kits (2)

Proteins (2)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Over-Expression Lysate (2)

Primary (44)

Target

KCNJ3 / GIRK1 (48)

Reactivity

Human (45)

Mouse (25)

Rat (21)

Bat (3)

Bovine (6)

Chicken (2)

Dog (2)

Gibbon (3)

Guinea pig (4)

Hamster (1)

Horse (4)

Monkey (10)

Pig (4)

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Application

IHC (16)

IHC-P (6)

WB (38)

Flo (12)

ELISA (10)

ICC (2)

IF (26)

Peptide-ELISA (3)

Host

rabbit (26)

mouse (18)

Product Group

IHCPlus (1)

Isotype

IgG (16)

IgG1 (10)

IgG2b (6)

IgM (2)

Clonality

monoclonal mc (18)

polyclonal pc (26)

Clone

OTI1B1 (2)

OTI1C5 (2)

OTI1D3 (2)

OTI1G2 (2)

OTI1G3 (2)

OTI2E4 (2)

OTI2F2 (2)

OTI3E11 (2)

Format

96-Well Microplate (2)

Biotin Conjugated (2)

Carrier-free (8)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (38)

Epitope

aa279-501 (10)

aa361-410 (4)

pSer185 (3)

120-200 aa (2)

C-Terminus (2)

Internal (2)

aa390-418 (2)

Cytoplasmic Domain (1)

Phe181 (1)

aa151-200 (1)

aa248-501 (1)

p185 (1)

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Publications

No (48)

Sample Type

Adherent Cell Cultures (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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KCNJ3 / GIRK1 Antibody (clone OTI3E11) LS-C173669

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (OTI3E11) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI3E11, Carrier-free) LS-C786773

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI3E11) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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KCNJ3 / GIRK1 Antibody (clone OTI1G3) LS-C173691

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (OTI1G3) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI1G3, Carrier-free) LS-C786805

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI1G3) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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KCNJ3 / GIRK1 Antibody (phospho-Ser185) LS-C368387

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (pSer185) Antibody

Reactivity:

Chicken, Bovine, Mouse, Rat, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

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KCNJ3 / GIRK1 Antibody (Internal) LS-C368386

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Bovine, Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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IHC-plus™ KCNJ3 / GIRK1 Antibody (Internal) LS-A9569

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Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

KCNJ3 / GIRK1 Antibody (phospho-Ser185) LS-C822568

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (pSer185) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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KCNJ3 / GIRK1 Antibody (phospho-Ser185) LS-C199000

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (pSer185) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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KCNJ3 / GIRK1 Antibody (120-200 aa) LS-C381520

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

KCNJ3 / GIRK1 Antibody LS-C801771

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

KCNJ3 / GIRK1 Antibody (clone OTI1G2) LS-C173692

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (OTI1G2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI1G2, Carrier-free) LS-C786810

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI1G2) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

KCNJ3 / GIRK1 Antibody (clone OTI2E4) LS-C173698

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (OTI2E4) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI2E4, Carrier-free) LS-C786813

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI2E4) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

KCNJ3 / GIRK1 Antibody (clone OTI1B1) LS-C173689

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (OTI1B1) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI1B1, Carrier-free) LS-C786804

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI1B1) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

KCNJ3 / GIRK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99695

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.4 kDa

Price:

100 µg/$494

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KCNJ3 / GIRK1 Antibody LS-C499199

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

KCNJ3 / GIRK1 Antibody (C-Terminus) LS-C153450

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

Select

KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI1C5) LS-C337596

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (OTI1C5) Antibody

Reactivity:

Mouse, Dog, Rat, Human, Monkey

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

KCNJ3 / GIRK1 Antibody (aa279-501, clone OTI1C5, Carrier-free) LS-C786762

Antibody:

KCNJ3 / GIRK1 Mouse anti-Human Monoclonal (aa279-501) (Carrier-free) (OTI1C5) Antibody

Reactivity:

Mouse, Dog, Rat, Human, Monkey

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

KCNJ3 / GIRK1 Antibody (120-200 aa) LS-C384268

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

KCNJ3 / GIRK1 Antibody LS-C498036

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

KCNJ3 / GIRK1 Antibody (p185) LS-C822566

Antibody:

KCNJ3 / GIRK1 Rabbit anti-Human Polyclonal (p185) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

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