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KCNJ16 / Kir5.1

potassium inwardly-rectifying channel, subfamily J, member 16

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.

Gene Name: potassium inwardly-rectifying channel, subfamily J, member 16
Family/Subfamily: Ion Channel , Potassium channel - inward-rectifying
Synonyms: KCNJ16, BIR9, KIR5.1
Target Sequences: NM_018658 NP_061128.2 Q9NPI9

Publications (1)

1
The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression. Lena L Rosenbaek, Federica Petrillo, Miguel X van Bemmelen, Olivier Staub, Sathish K Murali, Robert A Fenton. Frontiers in physiology. 2022 September;13:971251. [Full Text Article] [PubMed:36160843] [PMC:PMC9490057]

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Proteins (7)
Over-Expression Lysate (6)
Recombinant (1)
KCNJ16 / Kir5.1 (7)
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GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (4)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
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47.8 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$215
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HEK 293 Cells
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100 µg/$710
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HEK 293 Cells
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100 µg/$710
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HEK 293 Cells
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47.8 kDa
100 µg/$494
KCNJ16 / Kir5.1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).