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KCNIP2 / KCHIP2
Kv channel interacting protein 2
KCNIP2 / KCHIP2 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
| Gene Name: | Kv channel interacting protein 2 |
| Family/Subfamily: | Ion Channel , Potassium channel - interacting protein |
| Synonyms: | KCNIP2, KCHIP2 |
| Target Sequences: | NM_014591 NP_055406.2 Q9NS61 |
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