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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNA2 / Kv1.2

potassium voltage-gated channel, shaker-related subfamily, member 2

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Gene Name: potassium voltage-gated channel, shaker-related subfamily, member 2
Family/Subfamily: Ion Channel , Potassium channel - Kv1 Shaker
Synonyms: KCNA2, HBK5, KV1.2, HuK4, MK2, NGK1, RBK2, HK4, HUKIV
Target Sequences: NM_004974 NP_004965.1 P16389

Publications (2)

1
Specific antibodies to the external vestibule of voltage-gated potassium channels block current. Zhou BY, Ma W, Huang XY. The Journal of general physiology. 1998 111:555-63. [PubMed:9524138] [PMC:PMC2217123]
2
Postsynaptic density-95 scaffolding of Shaker-type K channels in smooth muscle cells regulates the diameter of cerebral arteries. Joseph BK, Thakali KM, Pathan AR, Kang E, Rusch NJ, Rhee SW. The Journal of physiology. 2011 589:5143-52. [PubMed:21911612] [PMC:PMC3225670]

Filtered By: None
Target
KCNA2 / Kv1.2 (36)
Reactivity
Human (29)
Mouse (16)
Rat (23)
Bat (1)
Bovine (12)
Chicken (1)
Dog (12)
Guinea pig (1)
Hamster (1)
Horse (1)
Pig (12)
Rabbit (2)
Sheep (1)
Xenopus (11)
Zebrafish (10)
Application
IHC (18)
IHC-P (1)
WB (36)
ELISA (10)
ICC (6)
IF (9)
IP (6)
Host
rabbit (29)
mouse (7)
Isotype
IgG (10)
IgG2b,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (29)
Format
AP Conjugated (2)
APC Conjugated (2)
Biotin Conjugated (4)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (16)
Epitope
aa50-100 (10)
aa451-479 (8)
C-Terminus (3)
aa325-375 (1)
aa466-499 (1)
Publications
No (36)
Showing 1-25 of 36 results

KCNA2 / Kv1.2 Antibody (C-Terminus) LS-C46846
Rabbit Polyclonal to Mouse KCNA2 / Kv1.2
Mouse, Rat, Human
ELISA WB
Unconjugated
100µg 0.5mg/ml  $275.00

KCNA2 / Kv1.2 Antibody (aa50-100) LS-C143265
Rabbit Polyclonal to Rat KCNA2 / Kv1.2
Xenopus, Zebrafish, Pig, Rat, Mouse, Dog, Bovine, Human
ICC WB
Unconjugated
100µl 1mg/ml  $335.00
Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells. Nuclei (Blue) are counterstained using Hoechst 33258.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells. Nuclei (Blue) are counterstained using Hoechst 33258.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KCNA2 / Kv1.2 Antibody (aa50-100, DY488) LS-C143268
Rabbit Polyclonal to Rat KCNA2 / Kv1.2
Xenopus, Zebrafish, Pig, Rat, Mouse, Dog, Bovine, Human
ICC WB
DY488 Conjugated
100µl  $365.00
Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells. Nuclei (Blue) are counterstained using Hoechst 33258.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv1.2 Antibody - Detection of Kv1.2 (Green) in 293 human embryonic kidney cells. Nuclei (Blue) are counterstained using Hoechst 33258.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KCNA2 / Kv1.2 Antibody LS-C346378
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Mouse, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunofluorescence analysis of HeLa cells.
Western blot analysis of extracts of various cells.
Immunofluorescence analysis of HeLa cells.
Western blot analysis of extracts of various cells.

KCNA2 / Kv1.2 Antibody LS-C668097
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Human
ICC IF WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunofluorescence Image
Western blot Image
Immunofluorescence Image
Western blot Image

KCNA2 / Kv1.2 Antibody LS-C123955
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
Unconjugated
100µg 1mg/ml  $665.00

KCNA2 / Kv1.2 Antibody (HRP) LS-C547535
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
HRP Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (Biotin) LS-C527433
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
Biotin Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (FITC) LS-C537405
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
FITC Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (PE) LS-C655580
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
PE Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (APC) LS-C517810
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IF IHC WB
APC Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (AP) LS-C509413
Mouse Monoclonal (IgG2b,k) to Rat KCNA2 / Kv1.2
Rat
IHC WB
AP Conjugated
100µl  $845.00

KCNA2 / Kv1.2 Antibody (C-Terminus) LS-C153502
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

KCNA2 / Kv1.2 Antibody (aa451-479) LS-C329716
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

KCNA2 / Kv1.2 Antibody (aa451-479, HRP) LS-C540486
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
HRP Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479, Biotin) LS-C520325
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479, FITC) LS-C260845
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479, AP) LS-C260842
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479, APC) LS-C260843
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479, PE) LS-C260846
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

KCNA2 / Kv1.2 Antibody (aa451-479) LS-C165409
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
KCNA2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
KCNA2 Antibody western blot of CEM cell line lysates (35 ug/lane). The KCNA2 antibody detected the KCNA2 protein (arrow).
KCNA2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
KCNA2 Antibody western blot of CEM cell line lysates (35 ug/lane). The KCNA2 antibody detected the KCNA2 protein (arrow).

KCNA2 / Kv1.2 Antibody LS-C412324
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Rat, Human
IF WB
Unconjugated
100µl  $385.00

KCNA2 / Kv1.2 Antibody (C-Terminus) LS-C144747
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Human
IHC WB
Unconjugated
100µl  $365.00

KCNA2 / Kv1.2 Antibody LS-C752927
Rabbit Polyclonal (IgG) to Human KCNA2 / Kv1.2
Human
ELISA WB
Unconjugated
100µg  $335.00

KCNA2 / Kv1.2 Antibody LS-C26737
Rabbit Polyclonal to Human KCNA2 / Kv1.2
Mouse, Rat, Human
WB
Unconjugated
100µg  $355.00
Showing 1-25 of 36 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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