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KCNA1 / Kv1.1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
KCNA1 / Kv1.1 is a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
| Gene Name: | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) |
| Family/Subfamily: | Ion Channel , Potassium channel - Kv1 Shaker |
| Synonyms: | KCNA1, EA1, AEMK, HBK1, KV1.1, HUK1, RCK1, MK1, RBK1, MBK1 |
| Target Sequences: | NM_000217 NP_000208.2 Q09470 |
☰ Filters
Products
Antibodies
(37)
Proteins
(5)
Type
Over-Expression Lysate
(2)
Primary
(37)
Recombinant
(3)
Target
KCNA1 / Kv1.1
(42)
Reactivity
Human
(36)
Mouse
(15)
Rat
(14)
Bat
(3)
Chimpanzee
(3)
Dog
(4)
Gibbon
(3)
Horse
(3)
Monkey
(3)
Pig
(4)
Application
IHC
(12)
IHC-P
(3)
WB
(33)
ELISA
(21)
ICC
(1)
IF
(2)
IP
(1)
Peptide-ELISA
(2)
Host
rabbit
(35)
mouse
(2)
Product Group
PathPlus Neuro
(2)
Isotype
IgG
(26)
IgG2a,k
(1)
Clonality
monoclonal mc
(1)
polyclonal pc
(36)
Clone
2D8
(1)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(4)
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(4)
HRP Conjugated
(4)
PE Conjugated
(1)
Unconjugated
(23)
Epitope
aa172-201
(7)
aa179-228
(4)
230-310 aa, Internal
(1)
C-Terminus
(1)
Internal
(1)
aa239-288
(1)
aa256-305
(1)
aa298-343
(1)
aa465-481
(1)
Publications
No
(42)
Tag
6His, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Human
(4)
Source
293T Cells
(1)
E. coli
(1)
HEK 293 Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(2)
Neuroscience
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa239-288) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
KCNA1 / Kv1.1 Mouse anti-Human Monoclonal (2D8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST
82.9 kDa
10 µg/$479; 25 µg/$670
Neuroscience
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa256-305) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, WB
Unconjugated
200 µl/$468
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa465-481) Antibody
Mouse, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa172-201) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (aa298-343) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
50 µl/$321; 100 µl/$403
KCNA1 / Kv1.1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$575
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (230-310 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KCNA1 / Kv1.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Rat, Pig, Human
IP, WB
Unconjugated
100 µl/$299
Viewing 1-25
of 42
product results
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