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KANK1

KN motif and ankyrin repeat domains 1

Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity; the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia; the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading; the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Gene Name: KN motif and ankyrin repeat domains 1
Synonyms: KANK1, ANKRD15, CPSQ2, KANK, Ankyrin repeat domain 15, KIAA0172
Target Sequences: D79994 BAA11489.2 Q14678

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Products
Antibodies (15)
Primary (15)
KANK1 (15)
Human (15)
Mouse (4)
Bat (3)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
IHC (2)
IHC-P (3)
WB (14)
ELISA (9)
IF (2)
IP (1)
rabbit (8)
mouse (7)
Product Group
IHCPlus (1)
IgG (4)
IgG1,k (1)
IgG2a,k (6)
monoclonal mc (7)
polyclonal pc (8)
1773CT634.49.61 (1)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (7)
C-Terminus (3)
aa1302-1352 (1)
aa302-351 (1)
aa701-800 (1)
No (15)
KANK1 Antibody - Anti-KANK1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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KANK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
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KANK1 Rabbit anti-Human Polyclonal (aa1302-1352) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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KANK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
KANK1 Antibody - KANK1 Antibody staining KANK1 in human heart tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
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KANK1 Mouse anti-Human Monoclonal (1773CT634.49.61) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
200 µl/$393
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KANK1 Mouse anti-Human Monoclonal (aa701-800) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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KANK1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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KANK1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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KANK1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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KANK1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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KANK1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
KANK1 Antibody - KANK1 antibody Western Blot of HCT15. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KANK1 Rabbit anti-Human Polyclonal (aa302-351) Antibody
Human
WB
Unconjugated
100 µl/$424
KANK1 Antibody - KANK1 antibody Western Blot of HCT15. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KANK1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
KANK1 Antibody - KANK1 antibody Western Blot of HCT15. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KANK1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
KANK1 Antibody - KANK1 antibody Western Blot of HCT15. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KANK1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
KANK1 Antibody - Immunochemical staining of human KANK1 in human stomach with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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KANK1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Viewing 1-15 of 15 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).