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JUN / c-Jun

jun proto-oncogene

c-Jun is a component of the transcription factor activator protein 1 (AP-1) that binds to and activates transcription at TRE/AP-1 elements. Phosphorylation of c-Jun at Ser 63/73, resulting in activation and c-Jun dependent transcription, occurs in response to extra or intracellular signals, including UV irradiation, growth factors and transforming oncoproteins.

Gene Name: jun proto-oncogene
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: JUN, Activator protein 1, AP-1, C-Jun, Jun proto-oncogene, p39, Jun oncogene, Proto-oncogene c-Jun, AP1, Enhancer-binding protein AP1, G0s7, Transcription factor AP-1, v-jun
Target Sequences: NM_002228 NP_002219.1 P05412

Publications (3)

1
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos. Liao G, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY. Proceedings of the National Academy of Sciences of the United States of America. 2006 103:16313-8. (WB) [PubMed:17060633] [PMC:PMC1637579]
2
Clara cells protein, prolactin and transcription factors of protein NF-?B and c-Jun/AP-1 levels in rats inhaled to stainless steel welding dust and its soluble form. Halatek T, Stanislawska M, Swiercz R, Domeradzka-Gajda K, Kuras R, Wasowicz W. International Journal of Occupational Medicine and Environmental Health. 2018 October;31:613-632. [Full Text Article] [PubMed:30283154]
3
HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy. Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Jurgen C Becker, Dirk Schadendorf, Edward Seto, Vernon K Sondak, John M Koomen, Yian A Chen, Eric K Lau, Lixin Wan, Jonathan D Licht, Keiran S M Smalley. Cancer research. 2019 June;79:2947-2961. [Full Text Article] [PubMed:30987999] [PMC:PMC6548652]

☰ Filters
Products
ELISA Kits (34)
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Cell-Based Phosphorylation (8)
Custom (6)
DNA Binding (1)
DNA Binding Phosphorylation (7)
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JUN / c-Jun (34)
Human (21)
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96-Well Microplate (11)
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JUN / c-Jun ELISA Kit
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DNA Binding
12 x 8-Well Microstrips
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
JUN / c-Jun ELISA Kit
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DNA Binding Phosphorylation
12 x 8-Well Microstrips
Human
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$735
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Microplate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
JUN / c-Jun ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
JUN / c-Jun ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
JUN / c-Jun ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
JUN / c-Jun ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
JUN / c-Jun ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
JUN / c-Jun ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$923
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
JUN / c-Jun ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
JUN / c-Jun ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).