JMY

junction mediating and regulatory protein, p53 cofactor

Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location.

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Products

Antibodies (31)

Type

Primary (31)

Target

JMY (31)

Reactivity

Human (31)

Mouse (8)

Bovine (1)

Chicken (4)

Chimpanzee (3)

Dog (1)

Monkey (3)

Pig (1)

Application

IHC (6)

IHC-P (5)

WB (25)

ELISA (17)

IF (3)

IP (1)

Peptide-ELISA (2)

Host

rabbit (25)

mouse (6)

Product Group

IHCPlus (2)

Isotype

IgG (18)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (25)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (15)

Epitope

aa2-29 (7)

aa30-79 (4)

aa1-50 (2)

900-980 aa, C-terminal (1)

C-Terminus (1)

aa163-341 (1)

aa535-635 (1)

aa800-850 (1)

aa931-980 (1)

Publications

No (31)

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IHC-plus™ JMY Antibody (aa931-980) LS-B9885

(4.0) Rating

Antibody:

JMY Rabbit anti-Human Polyclonal (aa931-980) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ JMY Antibody (aa1-50) LS-B14439

(4.0) Rating

Antibody:

JMY Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP

Format:

Unconjugated

Price:

50 µl/$460

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JMY Antibody LS-C666528

Antibody:

JMY Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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JMY Antibody LS-C674626

Antibody:

JMY Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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JMY Antibody LS-C804445

Antibody:

JMY Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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JMY Antibody (C-Terminus) LS-C356137

Antibody:

JMY Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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JMY Antibody (aa535-635) LS-C308560

Antibody:

JMY Mouse anti-Human Monoclonal (aa535-635) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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JMY Antibody (HRP) LS-C542799

Antibody:

JMY Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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JMY Antibody (Biotin) LS-C522666

Antibody:

JMY Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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JMY Antibody (FITC) LS-C532711

Antibody:

JMY Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

JMY Antibody (PE) LS-C650913

Antibody:

JMY Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

JMY Antibody (APC) LS-C514452

Antibody:

JMY Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

JMY Antibody (aa1-50) LS-C286924

Antibody:

JMY Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

JMY Antibody (aa2-29) LS-C322338

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

JMY Antibody (aa2-29, Biotin) LS-C236677

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

JMY Antibody (aa2-29, FITC) LS-C236678

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

JMY Antibody (aa2-29, APC) LS-C236675

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

JMY Antibody (aa2-29, PE) LS-C236680

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

JMY Antibody (aa2-29, Azide-free, HRP) LS-C249290

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

JMY Antibody (aa163-341) LS-C178717

Antibody:

JMY Rabbit anti-Human Polyclonal (aa163-341) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

JMY Antibody (900-980 aa, C-terminal) LS-C384219

Antibody:

JMY Rabbit anti-Human Polyclonal (900-980 aa, C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

JMY Antibody LS-C822418

Antibody:

JMY Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

JMY Antibody (aa800-850) LS-C289304

Antibody:

JMY Rabbit anti-Human Polyclonal (aa800-850) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

JMY Antibody (aa30-79) LS-C151822

Antibody:

JMY Rabbit anti-Human Polyclonal (aa30-79) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

JMY Antibody (aa2-29) LS-C157842

Antibody:

JMY Rabbit anti-Human Polyclonal (aa2-29) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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