JMJD6 / PSR

jumonji domain containing 6

Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. Has no histone lysine demethylase activity. Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation: required for angiogenic sprouting by regulating the pre-mRNA splicing activity of U2AF2/U2AF65. Seems to be necessary for the regulation of macrophage cytokine responses.

☰ Filters

Products

Proteins (10)

Type

Over-Expression Lysate (4)

Recombinant (6)

Target

JMJD6 / PSR (10)

Publications

No (10)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (8)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

Human JMJD6 / PSR Protein (Recombinant GST, N-terminus) (aa2-100) - LS-G61942

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human JMJD6 / PSR Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67486

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.4 kDa

Price:

20 µg/$1,107

Select

Human JMJD6 / PSR Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67488

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.3 kDa

Price:

20 µg/$1,107

Select

Human JMJD6 / PSR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79963

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.4 kDa

Price:

20 µg/$150

Select

Human JMJD6 / PSR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79964

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.3 kDa

Price:

20 µg/$150

Select

Human JMJD6 / PSR Protein (Recombinant GST) (Full Length) - LS-G32767

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.9 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human JMJD6 / PSR Protein (Recombinant His-T7) (aa1-334) - LS-G24552

Source:

E. coli

Tag:

His-T7

Molecular Weight:

43.1 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

Select

Human JMJD6 / PSR Protein (Recombinant His) - LS-G3214

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

Select

JMJD6 / PSR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119746

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.4 kDa

Price:

100 µg/$494

Select

JMJD6 / PSR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113424

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.3 kDa

Price:

100 µg/$494

Viewing 1-10 of 10 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.