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JCHAIN / Ig J Chain

immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.

Gene Name: immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Synonyms: JCHAIN, IGCJ, Immunoglobulin J chain, IGJ, IgJ chain, JCH
Target Sequences: M12759 AAA58902.1 P01591

Publications (2)

1
Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus. Tadaki Suzuki, Akira Kawaguchi, Akira Ainai, Shin-ichi Tamura, Ryo Ito, Pretty Multihartina, Vivi Setiawaty, Krisna Nur Andriana Pangesti, Takato Odagiri, Masato Tashiro, Hideki Hasegawa. Proceedings of the National Academy of Sciences of the United States of America. 2015 June;112:7809-14. [Full Text Article] [PubMed:26056267] [PMC:PMC4485102] Related Antibodies: LS-C666347.
2
Human Fc Receptor-like 3 Inhibits Regulatory T Cell Function and Binds Secretory IgA. Stuti Agarwal, Zachary Kraus, Jessica Dement-Brown, Oyeleye Alabi, Kyle Starost, Mate Tolnay. Cell reports. 2020 February;30:1292-1299.e3. [Full Text Article] [PubMed:32023449] Related Antibodies: LS-C666347.

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
JCHAIN / Ig J Chain (10)
No (10)
10His, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
His (2)
MBP, N-terminus + 6His, C-terminus (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (2)
293T Cells (1)
Baculovirus (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (7)
JCHAIN / Ig J Chain Protein
Select
Human JCHAIN / Ig J Chain Protein (Recombinant His) - LS-G2256
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
JCHAIN / Ig J Chain Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mouse JCHAIN / Ig J Chain Protein (Recombinant 6His-SUMO, N-terminus) (aa22-159) - LS-G56345
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Human JCHAIN / Ig J Chain Protein (Recombinant His) (Gln23-Asp159) - LS-G97573
E. coli
His
17 kDa
100 µg/$483
JCHAIN / Ig J Chain Protein - 12.5% SDS-PAGE of human IGJ stained with Coomassie Blue
Select
Human JCHAIN / Ig J Chain Protein (Recombinant GST) (Full Length) - LS-G29017
Wheat Germ Extract
GST
43.23 kDa
10 µg/$479; 25 µg/$670
JCHAIN / Ig J Chain Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
Human JCHAIN / Ig J Chain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76749
293T Cells
Myc-DDK (Flag)
17.9 kDa
20 µg/$150
JCHAIN / Ig J Chain Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mouse JCHAIN / Ig J Chain Protein (Recombinant 6His, N-terminus) (aa22-159) - LS-G57196
Yeast
6His, N-terminus
100 µg/$499; 20 µg/$364; 1 mg/$1,683
JCHAIN / Ig J Chain Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Human JCHAIN / Ig J Chain Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (aa23-159) - LS-G56346
E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
JCHAIN / Ig J Chain Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Human JCHAIN / Ig J Chain Protein (Recombinant MBP, N-terminus + 6His, C-terminus) (aa23-159) - LS-G57422
Baculovirus
MBP, N-terminus + 6His, C-terminus
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
JCHAIN / Ig J Chain Protein - Purified recombinant protein JCHAIN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
Human JCHAIN / Ig J Chain Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66011
HEK 293 Cells
Myc-DDK (Flag)
17.9 kDa
20 µg/$1,107
JCHAIN / Ig J Chain Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
JCHAIN / Ig J Chain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102285
HEK 293 Cells
Myc-DDK (Flag)
17.9 kDa
100 µg/$494
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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