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IVNS1ABP / NS1-BP
NS1-binding Protein (NS1-BP) (IVNS1ABP)
Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines By similarity. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
| Gene Name: | NS1-binding Protein (NS1-BP) (IVNS1ABP) |
| Synonyms: | IVNS1ABP, ARA3, HSPC068, KIAA0850, NCX downstream gene 1, ND1, NS-1, NS1-binding protein, NS1BP, NS1, KLHL39, FLARA3, NS1-BP |
| Target Sequences: | NM_006469 NP_006460.2 Q9Y6Y0 |
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