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ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
ITPR3 is a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
| Gene Name: | inositol 1,4,5-trisphosphate receptor, type 3 |
| Family/Subfamily: | Ion Channel , Inositol 1,4,5-triphosphate receptor |
| Synonyms: | ITPR3, InsP3R3, IP3R, InsP3R type 3, InsP3R type III, IP3 receptor, IP3R 3, IP3R3, Type 3 InsP3 receptor, IP3 receptor isoform 3 |
| Target Sequences: | NM_002224 NP_002215.2 Q14573 |
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