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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITPK1

inositol-tetrakisphosphate 1-kinase

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca2+-activated Cl- channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Gene Name: inositol-tetrakisphosphate 1-kinase
Synonyms: ITPK1, ITRPK1, Ins(1,3,4)P(3) 5/6-kinase
Target Sequences: NM_014216 NP_055031.2 Q13572

Filtered By: None
Target
ITPK1 (41)
Reactivity
Human (41)
Mouse (13)
Rat (9)
Bat (4)
Bovine (8)
Chimpanzee (6)
Dog (8)
Guinea pig (8)
Horse (8)
Monkey (4)
Pig (8)
Rabbit (8)
Application
IHC (3)
IHC-P (3)
WB (41)
ELISA (17)
ICC (1)
IF (1)
IP (1)
Peptide-ELISA (2)
Host
rabbit (33)
mouse (8)
Isotype
IgG (32)
IgG3,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (34)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (17)
Epitope
aa28-54 (8)
aa179-228 (4)
aa36-85 (4)
50-130 aa, Internal (1)
aa171-414 (1)
aa52-101 (1)
aa81-130 (1)
Publications
No (41)
Showing 1-25 of 41 results

ITPK1 Antibody (aa81-130) IHC-plus™ LS-B9944
Rabbit Polyclonal (IgG) to Human ITPK1
Mouse, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-ITPK1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HeLa, HepG2, and Jurkat cells, using ITPK1 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-ITPK1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from HeLa, HepG2, and Jurkat cells, using ITPK1 Antibody. The lane on the right is blocked with the synthesized peptide.

ITPK1 Antibody LS-C675922
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100

ITPK1 Antibody LS-C308555
Mouse Polyclonal (IgG) to Human ITPK1
Human
IF IHC IHC-P WB
Unconjugated
50µg  $560.00

ITPK1 Antibody (aa171-414) LS-C185926
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ICC WB
Unconjugated
100µl 0.53mg/ml  $335.00
Immunofluorescence of paraformaldehyde-fixed HeLa using ITPK1 antibody at 1:200 dilution.
Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. ITPK1 antibody diluted at 1:1000
Immunofluorescence of paraformaldehyde-fixed HeLa using ITPK1 antibody at 1:200 dilution.
Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. ITPK1 antibody diluted at 1:1000

ITPK1 Antibody LS-C308554
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
Unconjugated
100µg  $560.00

ITPK1 Antibody (HRP) LS-C542793
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
HRP Conjugated
100µl  $710.00

ITPK1 Antibody (Biotin) LS-C522661
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
Biotin Conjugated
100µl  $710.00

ITPK1 Antibody (FITC) LS-C532705
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
FITC Conjugated
100µl  $710.00

ITPK1 Antibody (PE) LS-C650904
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
PE Conjugated
100µl  $710.00

ITPK1 Antibody (AP) LS-C504736
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
AP Conjugated
100µl  $710.00

ITPK1 Antibody (APC) LS-C514445
Mouse Monoclonal (IgG3,k) to Human ITPK1
Human
ELISA WB
APC Conjugated
100µl  $710.00

ITPK1 Antibody (aa28-54) LS-C322310
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
Unconjugated
200µl  $530.00

ITPK1 Antibody (aa28-54, Biotin) LS-C215309
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

ITPK1 Antibody (aa28-54, FITC) LS-C215310
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
FITC Conjugated
200µl  $680.00

ITPK1 Antibody (aa28-54, AP) LS-C215307
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
AP Conjugated
200µl  $680.00

ITPK1 Antibody (aa28-54, APC) LS-C215308
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
APC Conjugated
200µl  $680.00

ITPK1 Antibody (aa28-54, Azide-free, HRP) LS-C215311
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

ITPK1 Antibody (aa28-54, PE) LS-C215312
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
PE Conjugated
200µl  $680.00

ITPK1 Antibody (50-130 aa, Internal) LS-C384193
Rabbit Polyclonal (IgG) to Human ITPK1
Mouse, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00

ITPK1 Antibody LS-C666513
Rabbit Polyclonal (IgG) to Human ITPK1
Human
ELISA WB
Unconjugated
100µg  $355.00

ITPK1 Antibody LS-C310803
Rabbit Polyclonal (IgG) to Human ITPK1
Human
IP WB
Unconjugated
100µl  $605.00

ITPK1 Antibody (aa52-101) LS-C292109
Rabbit Polyclonal (IgG) to Human ITPK1
Mouse, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of the lysates from HepG2 cells using ITPK1 antibody.
Western blot analysis of the lysates from HepG2 cells using ITPK1 antibody.

ITPK1 Antibody LS-C310806
Rabbit Polyclonal (IgG) to Human ITPK1
Human
WB
Unconjugated
100µg  $605.00

ITPK1 Antibody (aa36-85) LS-C81975
Rabbit Polyclonal (IgG) to Human ITPK1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human
WB
Unconjugated
50µg  $365.00
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ITPK1 Antibody (aa179-228) LS-C107845
Rabbit Polyclonal (IgG) to Human ITPK1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
50µg  $365.00
ITPK1 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
ITPK1 antibody Western blot of Fetal Spleen lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 41 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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