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ITGB8 / Integrin Beta 8
integrin, beta 8
ITGB8 / Integrin Beta 8 is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
| Gene Name: | integrin, beta 8 |
| Family/Subfamily: | Integrin , not assigned-Integrin |
| Synonyms: | ITGB8, Integrin beta-8 subunit, Integrin Beta 8, Integrin beta-8, Integrin, beta 8 |
| Target Sequences: | NM_002214 NP_002205.1 P26012 |
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