ITGB3 / Integrin Beta 3 / CD61

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

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Products

ELISA Kits (10)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (2)

Sandwich (5)

Target

ITGB3 / Integrin Beta 3 / CD61 (10)

Reactivity

Human (7)

Mouse (6)

Rat (2)

Format

96-Well Microplate (5)

96-Well Strip Plate (5)

Publications

No (10)

Sample Type

Adherent Cell Cultures (3)

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

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Human ITGB3 / Integrin Beta 3 / CD61 (Sandwich ELISA) ELISA Kit - LS-F33626

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Human ITGB3 / Integrin Beta 3 / CD61 (Sandwich ELISA) ELISA Kit - LS-F21226

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Mouse ITGB3 / Integrin Beta 3 / CD61 (Sandwich ELISA) ELISA Kit - LS-F8502

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$818

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Mouse ITGB3 / Integrin Beta 3 / CD61 (Custom ELISA) ELISA Kit - LS-F17787

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human ITGB3 / Integrin Beta 3 / CD61 (Custom ELISA) ELISA Kit - LS-F17786

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse ITGB3 / Integrin Beta 3 / CD61 (Sandwich ELISA) ELISA Kit - LS-F23527

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse/Human ITGB3 / Integrin Beta 3 / CD61 (Cell-Based ELISA) ELISA Kit - LS-F2083

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human ITGB3 / Integrin Beta 3 / CD61 (Sandwich ELISA) ELISA Kit - LS-F6638

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Mouse/Human/Rat Phospho-ITGB3 / Integrin Beta 3 / CD61 (Tyr773) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1538

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat Phospho-ITGB3 / Integrin Beta 3 / CD61 (Tyr785) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1539

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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