ITGB1 / Integrin Beta 1 / CD29

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion.

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Products

Proteins (18)

Type

Over-Expression Lysate (6)

Recombinant (12)

Target

ITGB1 / Integrin Beta 1 / CD29 (18)

Application

SDS-PAGE (1)

Publications

No (18)

Tag

6His, C-terminus (1)

6His, N-terminus (1)

GST (1)

His (1)

His,C-terminus (2)

His-GST (2)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (8)

Species

Human (12)

Mouse (2)

Rat (1)

Source

293T Cells (3)

E. coli (6)

HEK 293 Cells (7)

Human (1)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (3)

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His) (aa21-465) - LS-G2709

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His,C-terminus) (Met1-Asp728) - LS-G47926

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human ITGB1 consists 749 amino acids and predicts a molecular mass of 83.3 kDa.

Price:

50 µg/$403; 1 mg/$2,675

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Mouse ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant 6His, N-terminus) (aa21-728) - LS-G56356

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 10 µg/$328; 20 µg/$364

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Mouse ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His-T7) (aa454-714) - LS-G13292

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.5 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107546

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

100 µg/$710

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ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108167

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.6 kDa

Price:

100 µg/$710

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His,C-terminus) (Met1-Asp728) - LS-G140766

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

83.3 kDa

Price:

50 µg/$721

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant 6His, C-terminus) - LS-G145981

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

79.4 kDa

Price:

10 µg/$335; 50 µg/$615

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Rat ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His-SUMO) (aa21-729) - LS-G20882

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

94.4 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant GST) (Full Length) - LS-G29092

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

114.8 kDa

Price:

2 µg/$439

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75934

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

88.42 kDa

Price:

20 µg/$150

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75935

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.6 kDa

Price:

20 µg/$215

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75937

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

20 µg/$215

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65633

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

20 µg/$1,107

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65634

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

86.1 kDa

Price:

20 µg/$1,107

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ITGB1 / Integrin Beta 1 / CD29 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99692

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

88.42 kDa

Price:

100 µg/$494

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His-GST) (aa140-383) - LS-G13282

Source:

E. coli

Tag:

His-GST

Molecular Weight:

59.1 kDa

Price:

10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562

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Human ITGB1 / Integrin Beta 1 / CD29 Protein (Recombinant His-GST) (aa467-635) - LS-G13284

Source:

E. coli

Tag:

His-GST

Molecular Weight:

45.3 kDa

Price:

10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562

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