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ITGA2 / CD49b

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene Name: integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA2, Alpha2 integrin, BR, CD49b antigen, CD49B, Integrin alpha2, Integrin Alpha 2, Integrin alpha-2, HPA-5, VLA-2, VLAA2, VLA-2 subunit alpha, Collagen receptor, GPIa, Platelet antigen Br, Platelet glycoprotein GPIa, VLA2 receptor, alpha-2 subunit
Target Sequences: NM_002203 CAA34894.1 P17301

Publications (1)

1
Alpha2beta1 integrin regulates lineage commitment in multipotent human colorectal cancer cells. Kirkland SC, Ying H. The Journal of biological chemistry. 2008 283:27612-9. [PubMed:18664572] [PMC:PMC2562061]

☰ Filters
Products
Proteins (8)
Recombinant (8)
ITGA2 / CD49b (8)
No (8)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST, N-terminus (1)
His (1)
His-GST-S (1)
His-S (2)
His-T7 (1)
Bovine (1)
Human (6)
Mouse (1)
E. coli (6)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
Select
E. coli
His
25.1 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
ITGA2 / CD49b Protein - Recombinant  Integrin Alpha 2 By SDS-PAGE
Select
E. coli
His-T7
27.8 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
ITGA2 / CD49b Protein - Recombinant  Integrin Alpha 2 By SDS-PAGE
Select
E. coli
His-GST-S
47.5 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
ITGA2 / CD49b Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
ITGA2 / CD49b Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ITGA2 / CD49b Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ITGA2 / CD49b Protein - Recombinant Integrin Alpha 2 By SDS-PAGE
Select
E. coli
His-S
27.9 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
ITGA2 / CD49b Protein - Recombinant Integrin Alpha 2 By SDS-PAGE
Select
E. coli
His-S
26.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).