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ITGA1/CD49a/Integrin Alpha 1

integrin, alpha 1

The integrin alpha-1 chain associates with the integrin beta-1 chain to form a heterodimeric cell surface unit that functions as a receptor for laminin and collagen in neural cells and hematopoietic cells. It is involved in cell adhesion and neurite outgrowth. It may also play a role in inflammation and fibrosis.

Gene Name: integrin, alpha 1
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA1, CD49a antigen, CD49a, Integrin Alpha 1, Integrin, alpha 1, Integrin alpha-1, Laminin and collagen receptor, Very late activation protein 1, VLA1, VLA-1
Target Sequences: NM_181501 NP_852478.1 P56199

Publications (1)

1
Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation. Julia R Varshavsky, Joshua F Robinson, Yan Zhou, Kenisha A Puckett, Elaine Kwan, Sirirak Buarpung, Rayyan Aburajab, Stephanie L Gaw, Saunak Sen, Songmei Gao, Sabrina Crispo Smith, June-Soo Park, Igor Zakharevich, Roy R Gerona, Susan J Fisher, Tracey J Woodruff. Toxicological sciences : an official journal of the Society of Toxicology. 2021 May;181:215-228. [Full Text Article] [PubMed:33677611] [PMC:PMC8163039] Related Antibodies: LS-C36920.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).