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IRF6

interferon regulatory factor 6

IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Gene Name: interferon regulatory factor 6
Synonyms: IRF6, Interferon regulatory factor 6, OFC6, PPS1, VWS, VWS1, IRF-6, LPS, PIT, PPS, Van der Woude syndrome
Target Sequences: NM_006147 NP_006138.1 O14896

Publications (2)

1
Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. Chu EY, Tamasas B, Fong H, Foster BL, LaCourse MR, Tran AB, Martin JF, Schutte BC, Somerman MJ, Cox TC. Journal of dental research. 2016 October;95:1265-73. (Human) [Full Text Article] [PubMed:27369589] [PMC:PMC5076757] Related Antibodies: LS-B3231.
2
Hailey-Hailey disease: investigation of a possible compensatory SERCA2 up-regulation and analysis of SPCA1, p63, and IRF6 expression. Zhang D, Li X, Wang Z, Zhang Y, Guo K, Wang S, Tu C, Huo J, Xiao S. Archives of dermatological research. Mar;307:143-9. [Full Text Article] [PubMed:25256005] Related Antibodies: LS-B3231.

☰ Filters
Antibodies (63)
Proteins (7)
Over-Expression Lysate (2)
Primary (63)
Recombinant (5)
IRF6 (70)
Human (62)
Mouse (25)
Rat (17)
Bat (12)
Bovine (13)
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Chimpanzee (15)
Dog (20)
Drosophila (3)
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Guinea pig (9)
Hamster (12)
Horse (15)
Monkey (15)
Orangutan (12)
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Sheep (9)
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IHC (14)
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ICC (3)
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rabbit (48)
mouse (14)
goat (1)
Product Group
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IgG (18)
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IgG2b (6)
monoclonal mc (13)
polyclonal pc (50)
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UMAB106 (2)
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aa150-445 (8)
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aa455-467 (1)
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IRF6 Antibody - Anti-IRF6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IRF6 Goat anti-Human Polyclonal (aa455-467) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
IRF6 Antibody - Anti-IRF6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF6 Rabbit anti-Human Polyclonal (aa395-444) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
IRF6 Antibody - Anti-IRF6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF6 Rabbit anti-Human Polyclonal (aa395-444) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
IRF6 Antibody - Anti-IRF6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF6 Rabbit anti-Human Polyclonal (aa395-444) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
IRF6 Antibody - Anti-IRF6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF6 Rabbit anti-Human Polyclonal (aa395-444) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
IRF6 Antibody - IHC of paraffin-embedded Human breast tissue using anti-IRF6 mouse monoclonal antibody.
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IRF6 Mouse anti-Human Monoclonal (OTI2C10) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
IRF6 Antibody - IHC of paraffin-embedded Human breast tissue using anti-IRF6 mouse monoclonal antibody.
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IRF6 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C10) Antibody
Dog, Rat, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IRF6 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-IRF6 mouse monoclonal antibody.
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IRF6 Mouse anti-Human Monoclonal (OTI2A12) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
IRF6 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-IRF6 mouse monoclonal antibody.
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IRF6 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A12) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IRF6 Antibody - Western blot of recombinant IRF6.
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IRF6 Rabbit anti-Mouse Polyclonal (aa150-445) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IRF6 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IRF6 mouse monoclonal antibody.  heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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IRF6 Mouse anti-Human Monoclonal (UMAB106) Antibody
Dog, Human, Monkey
IF, IHC, WB
Unconjugated
100 µl/$493
IRF6 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IRF6 mouse monoclonal antibody.  heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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IRF6 Mouse anti-Human Monoclonal (Carrier-free) (UMAB106) Antibody
Dog, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
IRF6 Antibody - Anti-IRF6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6.
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IRF6 Mouse anti-Human Monoclonal (OTI1D4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
IRF6 Antibody - Anti-IRF6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6.
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IRF6 Mouse anti-Human Monoclonal (Carrier-free) (OTI1D4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
IRF6 Antibody - Anti-IRF6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6.
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IRF6 Mouse anti-Human Monoclonal (OTI1G3) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
IRF6 Antibody - Anti-IRF6 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6.
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IRF6 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G3) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
IRF6 Antibody - Immunofluorescent analysis of HepG2 cells using IRF6 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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IRF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
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IRF6 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
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IRF6 Mouse anti-Human Monoclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
IRF6 Antibody - Western blot of recombinant IRF6.
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IRF6 Rabbit anti-Human Polyclonal (aa196-445) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
IRF6 Antibody - Immunohistochemistry of paraffin-embedded rat pancreas.
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IRF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IRF6 Antibody - Immunohistochemical analysis of IRF-6 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IRF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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IRF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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IRF6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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IRF6 Rabbit anti-Human Polyclonal (Gly121) Antibody
Dog, Bovine, Human, Monkey
IP, WB
Unconjugated
100 µl/$688
Viewing 1-25 of 70 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).