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Unfortunately, the antibody (ID:201996) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



IRF3

interferon regulatory factor 3

Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.

Gene Name: interferon regulatory factor 3
Synonyms: IRF3, Interferon regulatory factor 3, IRF-3
Target Sequences: NM_001571 NP_001562.1 Q14653

Filtered By: None
Target
irf3 (113)
Reactivity
Human (95)
Mouse (39)
Rat (17)
African green monkey (1)
Bat (5)
Bovine (7)
Chimpanzee (3)
Dog (5)
Gibbon (3)
Guinea pig (4)
Horse (1)
Monkey (2)
Pig (8)
Sheep (5)
Application
IHC (14)
IHC-P (19)
WB (104)
Flo (6)
DB (2)
ELISA (45)
ICC (14)
IF (22)
IP (22)
Host
rabbit (84)
mouse (28)
goat (1)
Isotype
IgG (71)
IgG1 (12)
IgG1,k (2)
IgG2a (7)
IgG2a,k (1)
IgG2b (5)
Clonality
monoclonal mc (27)
polyclonal pc (86)
Clone
1522CT766.58.24 (1)
2G3 (1)
3C8 (1)
3F10 (1)
4D4 (1)
5D2 (1)
IRF35I218 (2)
JH73.1.1A10 (1)
JH73.1.1E11 (1)
JH73.1.2F9 (1)
JH73.1.4G8 (1)
JH73.1.5B12 (1)
JH73.1.6C2 (1)
JH73.2.1A4 (1)
JH73.2.1E3 (1)
JH73.2.1G7 (1)
JH73.2.3B2 (1)
JH73.2.6A11 (1)
JH73.2.6C8 (1)
JH73.2.6H10 (1)
JH74.1.6E9 (1)
JH98.1.3C12 (1)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (8)
FITC Conjugated (8)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (82)
Epitope
aa46-72 (8)
aa351-400 (5)
pSer385 (5)
pSer386 (4)
pSer396 (4)
C-Terminus (3)
aa1-360 (3)
aa1-406 (3)
aa108-166 (3)
aa100-150 (2)
Ala379 (1)
Internal (1)
Pro173 (1)
Val391 (1)
aa206-427 (1)
aa275-325 (1)
aa320-400 (1)
aa330-410 (1)
aa340-420 (1)
aa352-401 (1)
aa362-411 (1)
aa375-419 (1)
aa388-402 (1)
aa409-427 (1)
aa78-108 (1)
Publications
No (113)
Showing 1-25 out of 113 results
Anti-IRF3 Antibody (Internal) IHC-plus™ LS-B182

Rabbit Polyclonal to Human IRF3
Human
ICC IHC-P WB
Unconjugated
Anti-IRF3 Antibody (clone IRF35I218) LS-C184245

Mouse Monoclonal [clone IRF35I218] (IgG1) to Human IRF3
Human
DB Flo ICC IP WB
Unconjugated
Anti-IRF3 Antibody (phospho-Ser396) LS-C380923

Rabbit Polyclonal (IgG) to Human IRF3
Mouse, Rat, Human
ELISA WB
Unconjugated
Anti-IRF3 Antibody (C-Terminus) IHC-plus™ LS-B135

Rabbit Polyclonal to Human IRF3
Mouse, Human
IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (phospho-Ser385) LS-C199138

Rabbit Polyclonal (IgG) to Human IRF3
Human
ELISA IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (aa275-325) IHC-plus™ LS-B11648

Rabbit Polyclonal (IgG) to Mouse IRF3
Mouse, Human
IHC-P IP WB
Unconjugated
Anti-IRF3 Antibody IHC-plus™ LS-B2529

Rabbit Polyclonal (IgG) to Human IRF3
Human, Monkey
IHC-P WB
Unconjugated
Anti-IRF3 Antibody (phospho-Ser385) LS-C357142

Rabbit Polyclonal to Human IRF3
Mouse, Rat, Human
IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (aa108-166) LS-C45030

Mouse Monoclonal (IgG1) to Human IRF3
Human
ELISA WB
Unconjugated
Anti-IRF3 Antibody (clone IRF35I218) LS-C342311

Mouse Monoclonal [clone IRF35I218] (IgG1) to Human IRF3
Human
DB Flo ICC IF IP WB
Unconjugated
Anti-IRF3 Antibody (clone 1522CT766.58.24) LS-C392581

Mouse Monoclonal [clone 1522CT766.58.24] (IgG1,k) to Human IRF3
Human, African green monkey
ELISA Flo IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (clone 4D4) LS-C114575

Mouse Monoclonal [clone 4D4] (IgG2a) to Human IRF3
Flo IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody LS-C499144

Rabbit Polyclonal (IgG) to Human IRF3
Mouse, Human
ELISA IF IHC WB
Unconjugated
Anti-IRF3 Antibody (clone 3C8) LS-C197546

Mouse Monoclonal [clone 3C8] (IgG2a,k) to Human IRF3
Human
ELISA IF IP WB
Unconjugated
Anti-IRF3 Antibody LS-C417636

Rabbit Polyclonal to Human IRF3
Human
ICC IF IHC WB
Unconjugated
Anti-IRF3 Antibody (phospho-Ser385) LS-C416811

Rabbit Polyclonal to Human IRF3
Human
ICC IF IHC WB
Unconjugated
Anti-IRF3 Antibody (aa320-400) LS-C384188

Rabbit Polyclonal (IgG) to Human IRF3
Human
ELISA IF IHC WB
Unconjugated
Anti-IRF3 Antibody (phospho-Ser385) LS-C381472

Rabbit Polyclonal (IgG) to Human IRF3
Human
ELISA IF IHC WB
Unconjugated
Anti-IRF3 Antibody (C-Terminus) LS-C368606

Rabbit Polyclonal to Human IRF3
Mouse, Bovine, Pig, Human
ICC IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (C-Terminus) LS-C413182

Rabbit Polyclonal to Human IRF3
Mouse, Bovine, Pig, Human
ICC IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (aa351-400) LS-C117658

Rabbit Polyclonal (IgG) to Human IRF3
Human
ELISA IF IHC WB
Unconjugated
Anti-IRF3 Antibody LS-C70824

Mouse Monoclonal (IgG1) to Human IRF3
Human
Flo ICC IP WB
Unconjugated
Anti-IRF3 Antibody (aa206-427) LS-C36964

Goat Polyclonal (IgG) to Human IRF3
Human
ELISA Flo ICC WB
Unconjugated
Anti-IRF3 Antibody LS-C393406

Rabbit Polyclonal to Human IRF3
Mouse, Rat, Human
ICC IF IHC-P WB
Unconjugated
Anti-IRF3 Antibody (clone 2G3) LS-C114617

Mouse Monoclonal [clone 2G3] (IgG2a) to Human IRF3
Human
IF IHC-P WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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