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Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
Gene Name: | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
Synonyms: | IPPK, BA476B13.1 (novel protein), BA476B13.1, C9orf12, IP5K, INSP5K2, IPK1 homolog, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase, IPK1 |
Target Sequences: | NM_022755 NP_073592.1 Q9H8X2 |
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