IPO4

Importin 4

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus By similarity. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

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Products

Antibodies (12)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (12)

Recombinant (1)

Target

IPO4 (15)

Reactivity

Human (12)

Mouse (4)

Rat (2)

Bat (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Orangutan (3)

Application

IHC (7)

WB (9)

ELISA (4)

IF (3)

IP (3)

Peptide-ELISA (1)

Host

rabbit (12)

Isotype

IgG (7)

Clonality

polyclonal pc (12)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (9)

Epitope

aa468-517 (4)

aa136-289 (1)

aa350-400 (1)

aa900-950 (1)

Publications

No (15)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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IPO4 Antibody LS-C401777

Antibody:

IPO4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IPO4 Antibody LS-C666478

Antibody:

IPO4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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IPO4 Antibody LS-C802713

Antibody:

IPO4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IPO4 Antibody LS-C405084

Antibody:

IPO4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IPO4 Antibody (aa136-289) LS-C178633

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa136-289) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

IPO4 Antibody (aa350-400) LS-C289443

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa350-400) Antibody

Reactivity:

Human

Applications:

IHC, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

IPO4 Antibody (aa900-950) LS-C289446

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa900-950) Antibody

Reactivity:

Human

Applications:

IHC, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

IPO4 Antibody LS-C833502

Antibody:

IPO4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

IPO4 Antibody (aa468-517) LS-C169997

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa468-517) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

IPO4 Antibody (aa468-517, HRP) LS-C475254

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa468-517) (HRP) Antibody

Reactivity:

Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

IPO4 Antibody (aa468-517, Biotin) LS-C475252

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa468-517) (Biotin) Antibody

Reactivity:

Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

IPO4 Antibody (aa468-517, FITC) LS-C475253

Antibody:

IPO4 Rabbit anti-Human Polyclonal (aa468-517) (FITC) Antibody

Reactivity:

Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human IPO4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83784

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

118.5 kDa

Price:

20 µg/$150

Select

IPO4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109864

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

118.5 kDa

Price:

100 µg/$494

Select

Human IPO4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

118.5 kDa

Price:

20 µg/$1,107

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