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IOP1 / NARFL

nuclear prelamin A recognition factor-like

Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.

Gene Name:	nuclear prelamin A recognition factor-like
Synonyms:	NARFL, HPRN, IOP1, LET1L, PRN, Protein related to Narf, LET1 like/JFP15
Target Sequences:	NM_022493 NP_071938.1 Q9H6Q4

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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