INVS / Inversin

inversin

Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis.

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Products

Antibodies (17)

Proteins (8)

Type

Over-Expression Lysate (4)

Primary (17)

Recombinant (4)

Target

INVS / Inversin (25)

Reactivity

Human (17)

Mouse (3)

Rat (9)

Application

IHC (2)

IHC-P (1)

WB (14)

ELISA (6)

IF (2)

Peptide-ELISA (1)

Host

rabbit (17)

Isotype

IgG (7)

Clonality

polyclonal pc (17)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa1-237 (8)

Publications

No (25)

Tag

GST (2)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (2)

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INVS / Inversin Antibody LS-C678365

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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INVS / Inversin Antibody (HRP) LS-C678366

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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INVS / Inversin Antibody (Biotin) LS-C678363

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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INVS / Inversin Antibody (FITC) LS-C678367

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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INVS / Inversin Antibody LS-C753544

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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INVS / Inversin Antibody LS-C780230

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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INVS / Inversin Antibody LS-C810109

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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INVS / Inversin Antibody LS-C668408

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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INVS / Inversin Antibody LS-C497005

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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INVS / Inversin Antibody (aa1-237) LS-C374532

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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INVS / Inversin Antibody (aa1-237, HRP) LS-C711630

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (HRP) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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INVS / Inversin Antibody (aa1-237, Biotin) LS-C687216

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (Biotin) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

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INVS / Inversin Antibody (aa1-237, FITC) LS-C694020

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (FITC) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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INVS / Inversin Antibody (aa1-237, APC) LS-C717875

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (APC) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

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INVS / Inversin Antibody (aa1-237, PE) LS-C725692

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (PE) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

INVS / Inversin Antibody (aa1-237, APC, Cy7) LS-C734642

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (APC, Cy7) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

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INVS / Inversin Antibody (aa1-237, Cy3) LS-C702607

Antibody:

INVS / Inversin Rabbit anti-Human Polyclonal (aa1-237) (Cy3) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE
• APC, Cy7
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE
  • APC, Cy7
  • Cy3

Select

INVS / Inversin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113956

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.6 kDa

Price:

100 µg/$710

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INVS / Inversin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104005

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.4 kDa

Price:

100 µg/$710

Select

Human INVS / Inversin Protein (Recombinant His-T7) (aa1-237) - LS-G24930

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.0 kDa

Price:

10 µg/$275; 50 µg/$407; 100 µg/$650; 200 µg/$812; 1 mg/$1,891; 500 µg/$1,443; 5 mg/$2,836; 2 mg/$2,075

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Human INVS / Inversin Protein (Recombinant GST) (Full Length) - LS-G33268

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.85 kDa

Price:

10 µg/$479; 25 µg/$670

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Human INVS / Inversin Protein (Recombinant GST) (Full Length) - LS-G33269

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.1 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human INVS / Inversin Protein (Recombinant GST, N-terminus) (aa1-91) - LS-G62240

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human INVS / Inversin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84535

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

117.6 kDa

Price:

20 µg/$215

Select

Human INVS / Inversin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84536

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.4 kDa

Price:

20 µg/$215

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