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INT7 / INTS7
integrator complex subunit 7
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase.
| Gene Name: | integrator complex subunit 7 |
| Synonyms: | INTS7, Integrator complex subunit 7, C1orf73, DKFZP434B168, INT7 |
| Target Sequences: | NM_015434 NP_056249.1 Q9NVH2 |
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