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INSIG2

insulin induced gene 2

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Gene Name: insulin induced gene 2
Synonyms: INSIG2, Insulin induced protein 2, INSIG2 membrane protein, Insulin-induced gene 2 protein, INSIG-2, Insulin induced gene 2
Target Sequences: AF125392 Q9Y5U4 Q9Y5U4

☰ Filters
Products
Antibodies (8)
Primary (8)
INSIG2 (8)
Human (8)
Mouse (3)
Rat (2)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Goat (3)
Horse (3)
Monkey (3)
Rabbit (3)
IHC (2)
WB (8)
ELISA (2)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (8)
IgG (7)
polyclonal pc (8)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (5)
N-Terminus (4)
No (8)
INSIG2 Antibody - Western blot analysis INSIG2 using HeLa whole cells lysates
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INSIG2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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INSIG2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
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INSIG2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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INSIG2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
INSIG2 Antibody - INSIG2 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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INSIG2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
INSIG2 Antibody - INSIG2 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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INSIG2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Goat, Bovine, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
INSIG2 Antibody - INSIG2 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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INSIG2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Goat, Bovine, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
INSIG2 Antibody - INSIG2 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
INSIG2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Goat, Bovine, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).