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INPP5B is a member of a family of inositol polyphosphate-5-phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Alternatively spliced transcript variants of this gene have been described.
Gene Name: | inositol polyphosphate-5-phosphatase, 75kDa |
Family/Subfamily: | Inositol Phosphatase , not assigned-Inositol Phosphatase |
Synonyms: | INPP5B, 5PTASE, OCRL2, Phosphoinositide 5-phosphatase |
Target Sequences: | M74161 AAA79207.1 P32019 |
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