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INHBB / Inhibin Beta B

inhibin, beta B

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Gene Name: inhibin, beta B
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: INHBB, Activin beta-B chain, Activin AB beta polypeptide, Inhibin, beta B, Inhibin Beta B, Inhibin beta B chain, Inhibin, beta-2
Target Sequences: NM_002193 NP_002184.2 P09529

Publications (1)

1
Inhibin B in seminiferous tubules of human testes in normal spermatogenesis and in idiopathic infertility. Grigory A Demyashkin. Systems biology in reproductive medicine. 2019 Feb;65:20-28. [Full Text Article] [PubMed:29886763]

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ELISA Kits (13)
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INHBB / Inhibin Beta B (13)
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Mouse (3)
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12 x 8-Well Microstrips (1)
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96-Well Strip Plate (11)
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Yes (1)
Plasma (9)
Serum (9)
Tissue Homogenates (3)
INHBB / Inhibin Beta B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
INHBB / Inhibin Beta B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
INHBB / Inhibin Beta B ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
INHBB / Inhibin Beta B ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
INHBB / Inhibin Beta B ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
INHBB / Inhibin Beta B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
INHBB / Inhibin Beta B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
INHBB / Inhibin Beta B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
INHBB / Inhibin Beta B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
INHBB / Inhibin Beta B ELISA Kit
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Competitive EIA
12 x 8-Well Microstrips
Dog
5 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
INHBB / Inhibin Beta B ELISA Kit
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Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$588
INHBB / Inhibin Beta B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
INHBB / Inhibin Beta B ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).