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ING2

inhibitor of growth family, member 2

Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

Gene Name:	inhibitor of growth family, member 2
Synonyms:	ING2, ING1Lp, Inhibitor of growth protein 2, p33ING2, p32, ING1L
Target Sequences:	NM_001564 NP_001555.1 Q9H160

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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