Influenza B Matrix M1

Influenza B Matrix M1 plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.

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Products

Antibodies (3)

Type

Primary (3)

Target

Influenza B Matrix M1 (3)

Reactivity

Influenza Virus (2)

Virus (1)

Application

WB (3)

ELISA (3)

Host

mouse (3)

Product Group

Influenza B Virus (3)

Orthomyxoviridae (3)

Isotype

IgG1 (3)

Clonality

monoclonal mc (3)

Clone

InB15 (1)

InB4 (2)

Format

Unconjugated (3)

Publications

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Influenza B Matrix M1 Antibody (clone InB4) LS-C188412

Antibody:

Influenza B Matrix M1 Mouse anti-Virus Monoclonal (InB4) Antibody

Reactivity:

Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.2 mg/$486

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Influenza B Matrix M1 Antibody (clone InB4) LS-C52252

Antibody:

Influenza B Matrix M1 Mouse anti-Influenza Virus Monoclonal (InB4) Antibody

Reactivity:

Influenza Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.2 mg/$423; 0.5 mg/$503

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Influenza B Matrix M1 Antibody (clone InB15) LS-C52253

Antibody:

Influenza B Matrix M1 Mouse anti-Influenza Virus Monoclonal (InB15) Antibody

Reactivity:

Influenza Virus

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.2 mg/$423; 0.5 mg/$503

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