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INF2
inverted formin, FH2 and WH2 domain containing
This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.
| Gene Name: | inverted formin, FH2 and WH2 domain containing |
| Synonyms: | INF2, C14orf151, C14orf173, FSGS5, Inverted formin-2, Pp9484, CMTDIE, HBEBP2-binding protein C |
| Target Sequences: | NM_001031714 NP_001026884.3 |
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