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IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Gene Name: IMP (inosine 5'-monophosphate) dehydrogenase 1
Synonyms: IMPDH1, IMP dehydrogenase 1, IMPD 1, IMPDH 1, IMPD1, LCA11, IMPD, IMPDH-I, SWSS2608, RP10
Target Sequences: NM_000883 NP_000874.2 P20839

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Products
Antibodies (36)
Primary (36)
IMPDH1 (36)
Human (36)
Mouse (11)
Rat (11)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (3)
Horse (6)
Monkey (6)
Orangutan (3)
Pig (6)
Rabbit (3)
Xenopus (6)
Zebrafish (6)
IHC (22)
IHC-P (7)
WB (31)
ELISA (20)
ICC (5)
IF (8)
IP (1)
Peptide-ELISA (1)
rabbit (34)
mouse (2)
Product Group
IHCPlus (3)
IgG (28)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (35)
3G6 (1)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (17)
aa487-514 (7)
aa84-113 (7)
aa254-303 (4)
aa479-528 (4)
No (36)
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH1 Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH1 Rabbit anti-Human Polyclonal (aa254-303) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH1 Rabbit anti-Human Polyclonal (aa254-303) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IMPDH1 Rabbit anti-Human Polyclonal (aa254-303) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
IMPDH1 Antibody - Immunohistochemistry Dilution at 1:600 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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IMPDH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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IMPDH1 Rabbit anti-Human Polyclonal (aa487-514) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
IMPDH1 Antibody - Anti-IMPDH1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
IMPDH1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using IMPDH1 Polyclonal Antibody at dilution of 1:20.
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IMPDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IMPDH1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using IMPDH1 Polyclonal Antibody at dilution of 1:20.
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IMPDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
IMPDH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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IMPDH1 Rabbit anti-Human Polyclonal (aa84-113) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
IMPDH1 Antibody - IMPDH1 monoclonal antibody (M01), clone 3G6. Western Blot analysis of IMPDH1 expression in HeLa.
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IMPDH1 Mouse anti-Human Monoclonal (3G6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
IMPDH1 Antibody - Western blot analysis of extracts of 3T3 cells using IMPDH1 antibody. The lane on the left was treated with blocking peptide.
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IMPDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IMPDH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).