IMPA1 / IMP

inositol(myo)-1(or 4)-monophosphatase 1

IMPA1 / IMP is an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.

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Antibodies (19)

Proteins (11)

ELISA Kits (6)

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Custom (4)

Over-Expression Lysate (4)

Primary (19)

Recombinant (7)

Sandwich (2)

Target

IMPA1 / IMP (36)

Reactivity

Human (21)

Mouse (15)

Rat (8)

Guinea pig (3)

Monkey (3)

Orangutan (3)

Pig (1)

Rabbit (3)

Application

IHC (4)

WB (18)

Flo (1)

ELISA (5)

ICC (1)

IF (3)

IP (2)

Host

rabbit (17)

mouse (2)

Isotype

IgG (13)

IgG1,k (2)

Clonality

monoclonal mc (2)

polyclonal pc (17)

Clone

1E6-F11 (1)

AT2G5 (1)

Format

96-Well Strip Plate (6)

APC Conjugated (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (11)

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aa227-277 (1)

aa25-75 (1)

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No (36)

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Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, N-terminus (2)

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His (2)

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Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

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Low Endotoxin Level

Low endotoxin level (2)

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IMPA1 / IMP Antibody LS-C666437

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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IMPA1 / IMP Antibody LS-C334674

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IMPA1 / IMP Antibody (clone AT2G5) LS-C755491

Antibody:

IMPA1 / IMP Mouse anti-Human Monoclonal (AT2G5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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Mouse IMPA1 / IMP (Sandwich ELISA) ELISA Kit - LS-F17125

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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IMPA1 / IMP Antibody LS-C767557

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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IMPA1 / IMP Antibody LS-C830482

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IMPA1 / IMP Antibody (clone 1E6-F11) LS-C197531

Antibody:

IMPA1 / IMP Mouse anti-Human Monoclonal (1E6-F11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$423

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IMPA1 / IMP Antibody LS-C831984

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IMPA1 / IMP Antibody (aa227-277) LS-C762942

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (aa227-277) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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IMPA1 / IMP Antibody LS-C311280

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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IMPA1 / IMP Antibody (HRP) LS-C542727

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (Biotin) LS-C522594

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (FITC) LS-C532639

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (APC) LS-C514380

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (PE) LS-C650840

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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IMPA1 / IMP Antibody (C-Terminus) LS-C112233

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IMPA1 / IMP Antibody (C-Terminus, HRP) LS-C465074

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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IMPA1 / IMP Antibody (C-Terminus, Biotin) LS-C465072

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

IMPA1 / IMP Antibody (C-Terminus, FITC) LS-C465073

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

IMPA1 / IMP Antibody (aa25-75) LS-C762946

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (aa25-75) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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Human IMPA1 / IMP Protein (Recombinant GST) - LS-G132226

Tag:

GST

Molecular Weight:

31.35kDa

Price:

10 µg/$479; 25 µg/$670

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IMPA1 / IMP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126373

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

100 µg/$494

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IMPA1 / IMP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115904

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30 kDa

Price:

100 µg/$494

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Bovine IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17124

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Pig IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17126

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Viewing 1-25 of 36 product results

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