IMP-3 / IGF2BP3

insulin-like growth factor 2 mRNA binding protein 3

RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

IMP-3 / IGF2BP3 (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human IMP-3 / IGF2BP3 Protein (Recombinant 6His, N-terminus) (Asn2-Lys579) - LS-G26548

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

66 kDa

Price:

10 µg/$265; 50 µg/$315; 200 µg/$484

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IMP-3 / IGF2BP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115226

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.5 kDa

Price:

100 µg/$494

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Human IMP-3 / IGF2BP3 Protein (Recombinant GST) (Full Length) - LS-G32275

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

89.43 kDa

Price:

2 µg/$439

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Human IMP-3 / IGF2BP3 Protein (Recombinant His, N-Terminal) - LS-G144438

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

63.5 kDa

Price:

50 µg/$419

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Human IMP-3 / IGF2BP3 Protein (Recombinant His-T7) (aa2-343) - LS-G26122

Source:

E. coli

Tag:

His-T7

Molecular Weight:

41.5 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human IMP-3 / IGF2BP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81994

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.5 kDa

Price:

20 µg/$150

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