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ILKAP

integrin-linked kinase-associated serine/threonine phosphatase

Integrin-linked kinase-associated phosphatase 2C (ILKAP), a PP2C type serine/threonine phosphatase, is a monomeric enzyme composed of a catalytic and noncatalytic domain. The dephosphorylation catalytic activity is sensitive to manganese and magnesium. ILKAP has been found to associate with the integrin-linked kinase 1 (ILK1). It downregulates integrin and growth factor stimulated ILK1 activity. It is believed to target ILK1 signalling of the Wnt pathway via modulation of GSK3beta phosphorylation. Over-expression of ILKAP in mammalian cells has been found to result in inhibition of cell cycle progression.

Gene Name: integrin-linked kinase-associated serine/threonine phosphatase
Family/Subfamily: Protein Phosphatase , PP2C
Synonyms: ILKAP, DKFZP434J2031, ILKAP2, ILKAP3, pp2Cdelta, PP2C-DELTA
Target Sequences: NM_030768 NP_110395.1 Q9H0C8

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Products
Antibodies (36)
Primary (36)
ILKAP (36)
Human (36)
Mouse (19)
Rat (9)
Chimpanzee (3)
Gibbon (3)
Horse (3)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (15)
IHC-P (3)
WB (34)
ELISA (23)
IF (2)
IP (2)
Peptide-ELISA (2)
rabbit (33)
mouse (2)
sheep (1)
IgG (27)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (35)
3B5 (1)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (20)
aa243-270 (7)
aa93-122 (7)
aa310-359 (4)
10-90 aa, Internal (1)
aa1-392 (1)
aa41-90 (1)
aa50-100 (1)
No (36)
ILKAP Antibody - 1:100 staining human Smooth muscle tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ILKAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ILKAP Antibody - Western blot of ILKAP antibody
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ILKAP Rabbit anti-Human Polyclonal (10-90 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ILKAP Antibody - Immunoperoxidase of monoclonal antibody to ILKAP on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
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ILKAP Mouse anti-Human Monoclonal (3B5) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
ILKAP Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ILKAP Antibody. The picture on the right is blocked with the synthesized peptide.
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ILKAP Rabbit anti-Human Polyclonal (aa41-90) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ILKAP Antibody - ILKAP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa243-270) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ILKAP Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ILKAP antibody.
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ILKAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
ILKAP Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using ILKAP Polyclonal Antibody at dilution of 1:55(×200)
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ILKAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ILKAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
ILKAP Antibody - Western blot of COS7 cell lysate using ILKAP Antibody
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ILKAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
ILKAP Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using ILKAP Polyclonal Antibody at dilution of 1:50(×200)
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ILKAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ILKAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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ILKAP Rabbit anti-Human Polyclonal (aa93-122) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ILKAP Antibody - Western blot of Transcription initiation factor IIB antibody at 2 ug/ml lane 1: rat kidney tissue. lane 2: U251 whole cell lysate. Lane 3: mouse stomach tissue. Secondary: Goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 43.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ILKAP Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
ILKAP Antibody - Western blot of Transcription initiation factor IIB antibody at 2 ug/ml lane 1: rat kidney tissue. lane 2: U251 whole cell lysate. Lane 3: mouse stomach tissue. Secondary: Goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 43.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ILKAP Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 36 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).