Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IL8 / Interleukin 8

interleukin 8

Interleukin 8 (IL8), a member of the CXC chemokine family. This chemokine, is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

Gene Name: interleukin 8
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL8, 3-10C, AMCF-I, B-ENAP, C-X-C motif chemokine 8, GCP-1, IL-8, IL8, Interleukin-8, K60, LECT, GCP1, LUCT, NAF, NAP1, Neutrophil-activating factor, Interleukin 8, Protein 3-10C, MDNCF, TSG-1, Emoctakin, LYNAP, MONAP, NAP-1, SCYB8, T-cell chemotactic factor
Target Sequences: NM_000584 NP_000575.1 P10145

Publications (6)

1
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. de Jonge J, Kurian S, Shaked A, Reddy KR, Hancock W, Salomon DR, Olthoff KM. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2009 9:758-72. (IHC) [PubMed:19353763] [PMC:PMC2734955]
2
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112] Related Antibodies: LS-C104558.
3
Expression and secretion of the pro-inflammatory cytokine IL-8 is increased in colorectal cancer cells following the knockdown of non-erythroid spectrin aII. Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger. International journal of oncology. 2020 June;56:1551-1564. [Full Text Article] [PubMed:32236629] Related Antibodies: LS-C663556.
4
Free fatty acids promote degranulation of azurophil granules in neutrophils by inducing production of NADPH oxidase-derived reactive oxygen species in cows with subclinical ketosis. Yuxiang Song, Shang Jiang, Congyi Li, Juan J Loor, Qianming Jiang, Yuchen Yang, Xiancheng Feng, Siyuan Liu, Jiyuan He, Kexin Wang, Yunfei Li, Cai Zhang, Xiliang Du, Zhe Wang, Xinwei Li, Guowen Liu. Journal of dairy science. 2022 March;105:2473-2486. [Full Text Article] [PubMed:34998570]
5
LncRNA H19 aggravates TNF-a-induced inflammatory injury via TAK1 pathway in MH7A cells. Jialiang Yang, Yixuan Li, Lili Wang, Zhenchun Zhang, Zunzhong Li, Qian Jia. BioFactors (Oxford, England). 2020 September;46:813-820. [Full Text Article] [PubMed:32525617] Related Antibodies: LS-C104558.
6
Plexin-B1 activates NF- kappa B and IL-8 to promote a pro-angiogenic response in endothelial cells. Yang YH, Zhou H, Binmadi NO, Proia P, Basile JR. PloS one. 2011 6:e25826. [Full Text Article] [PubMed:22028792] [PMC:PMC3196529] Related Antibodies: LS-C8020.
more

☰ Filters
Products
Proteins (57)
Over-Expression Lysate (2)
Recombinant (53)
IL8 / Interleukin 8 (57)
Product Group
Coronavirus Antibodies Proteins cDNAs (57)
Cytokine Release Syndrome (57)
Cytokine Release Syndrome Proteins (57)
Animal-free (1)
No (57)
6His, C-terminus (3)
6His, N-terminus (3)
Fc (2)
GST (2)
GST, N-terminus (1)
His (11)
His, N-Terminal (1)
His-S (2)
His-T7 (3)
Human Mutant IgG1 Fc (1)
Myc-DDK (Flag) (3)
Chicken (3)
Cow (1)
Dog (4)
Guinea pig (1)
Horse (1)
Human (37)
Pig (3)
Rabbit (2)
Rhesus monkey (2)
Sheep (2)
293F Cells (1)
293T Cells (1)
CHO Cells (2)
E. coli (36)
HEK 293 Cells (2)
Human Cells (5)
Mammalian Cells (3)
Wheat Germ Extract (2)
Yeast (4)
Purified (21)
Low endotoxin level (26)
Biologically active (11)
Animal-free (1)
Select
E. coli
His
13 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
IL8 / Interleukin 8 Protein - Recombinant Interleukin 8 By SDS-PAGE
Select
E. coli
His-T7
12.9 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Select
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.9 kDa
5 µg/$268; 25 µg/$349
IL8 / Interleukin 8 Protein - Recombinant Pig interleukin-8 detected using Rabbit anti Pig interleukin-8 as the capture reagent and Rabbit anti Pig interleukin-8:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
9.1 kDa
5 µg/$390
IL8 / Interleukin 8 Protein - Rabbit Interleukin-8 ELISA : Recombinant Rabbit interleukin-8 detected using purified Goat anti Rabbit interleukin-8 as the capture reagent and biotinylated Goat anti Rabbit interleukin-8 as the detection reagent followed by horseradish peroxidase conjugated Streptavidin.
Select
Yeast
None
9.1 kDa
5 µg/$390
IL8 / Interleukin 8 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
10.9 kDa
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
None
Less than 0.01 EU/µg protein (determined by LAL method).
10.8 kDa
2 µg/$349; 10 µg/$718; 50 µg/$2,149; 100 µg/$3,596
Select
E. coli
None
Less than 0.01 EU/µg protein (determined by LAL method).
8.4 kDa
5 µg/$279; 20 µg/$354; 50 µg/$456; 100 µg/$634; 1000 µg/$2,337
IL8 / Interleukin 8 Protein - Eukaryotic Interleukin 8 (IL8) by SDS-PAGE
Select
293F Cells
His, N-Terminal
13kDa
10 µg/$278; 50 µg/$422; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
GST
36.5 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
E. coli
His
13.2 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
IL8 / Interleukin 8 Protein - 12.5% SDS-PAGE of human IL8 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
36.52 kDa
10 µg/$479; 25 µg/$670
IL8 / Interleukin 8 Protein
Select
Yeast
His
11.1 kD
1 mg/$1,973; 100 µg/$679; 20 µg/$429
IL8 / Interleukin 8 Protein
Select
E. coli
His
13.5 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
~9 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,612
Select
None
8.4 kD
25 µg/$484
IL8 / Interleukin 8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$439
IL8 / Interleukin 8 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, N-terminus
100 µg/$1,009; 20 µg/$431; 1 mg/$3,451
IL8 / Interleukin 8 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
None
1 mg/$1,756; 100 µg/$734; 20 µg/$488
IL8 / Interleukin 8 Protein - Purified recombinant protein CXCL8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
9.1 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
11.1 kDa
20 µg/$150
IL8 / Interleukin 8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
11.1 kDa
100 µg/$494
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
35 kDa
100 µg/$666
Select
CHO Cells
Human Mutant IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$389; 10 µg/$312
Select
E. coli
His
Less than 0.1 EU/µg protein (determined by LAL method).
50 µg/$541; 10 µg/$319
Viewing 1-25 of 57 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).