IL6ST / CD130 / gp130

interleukin 6 signal transducer (gp130, oncostatin M receptor)

IL6ST / CD130 / gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.

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Products

Proteins (16)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Recombinant (13)

Target

IL6ST / CD130 / gp130 (16)

Application

Bind (1)

ELISA (1)

Func (1)

SDS-PAGE (1)

Publications

No (16)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His,C-terminus (3)

His-Fc (2)

His-GST, N-terminus (1)

His-T7 (1)

Human IgG1 Fc, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Mouse (3)

Rat (4)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (8)

Human Cells (2)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (2)

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Human IL6ST / CD130 / gp130 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Glu23-Glu619) - LS-G26901

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

68 kDa

Price:

200 µl/$283

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Human IL6ST / CD130 / gp130 Protein (Recombinant GST, N-terminus) (aa23-122) - LS-G58976

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse IL6ST / CD130 / gp130 Protein (Recombinant His,C-terminus) (Met1-Glu617) - LS-G51300

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse gp130 consists of 606 amino acids and has a predicted molecular mass of 68 kDa. As a result of glycosylation, the apparent molecular mass of rm gp130 is approximately 80-90 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$426; 20 µg/$294; 1 mg/$1,869

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Human IL6ST / CD130 / gp130 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76925

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.54 kDa

Price:

20 µg/$215

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Human IL6ST / CD130 / gp130 Protein (Recombinant His, N-Terminal) (Glu23-Glu619) - LS-G96860

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

68 kDa (110 kDa reducing conditions)

Price:

10 µg/$289; 200 µg/$646; 50 µg/$360

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Human IL6ST / CD130 / gp130 Protein (Recombinant His) (aa606-756) - LS-G11365

Source:

E. coli

Tag:

His

Molecular Weight:

18.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat IL6ST / CD130 / gp130 Protein (Recombinant His-GST, N-terminus) (Glu26-Asp323) - LS-G132698

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

63.6kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat IL6ST / CD130 / gp130 Protein (Recombinant Human IgG1 Fc, N-terminus) - LS-G134300

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc, N-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 5.0 EU/mg protein (determined by LAL method).

Molecular Weight:

~120 kDa (SDS-PAGE)

Price:

50 µg/$442

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Rat IL6ST / CD130 / gp130 Protein (Recombinant His,C-terminus) (Met4-Glu618) - LS-G137966

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68.2 kDa

Price:

100 µg/$926

Select

Mouse IL6ST / CD130 / gp130 Protein (Recombinant His,C-terminus) (Met1-Glu617) - LS-G138516

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68 kDa

Price:

100 µg/$793; 20 µg/$458

Select

Human IL6ST / CD130 / gp130 Protein (Recombinant) (Met1-Ile618) - LS-G138470

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

68.6 kDa

Price:

200 µg/$1,244

Select

Mouse IL6ST / CD130 / gp130 Protein (Recombinant His-T7) (aa238-500) - LS-G23837

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.4 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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IL6ST / CD130 / gp130 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99683

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.54 kDa

Price:

100 µg/$710

Select

Human IL6ST / CD130 / gp130 Protein (Recombinant His-Fc) (Met1-Ile618) - LS-G97615

Source:

Human Cells

Tag:

His-Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

96 kDa

Price:

20 µg/$515; 100 µg/$1,007

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Human IL6ST / CD130 / gp130 Protein (Recombinant His) (aa392-566) - LS-G11367

Source:

E. coli

Tag:

His

Molecular Weight:

20.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

Select

Rat IL6ST / CD130 / gp130 Protein (Recombinant His-Fc) (Met4-Glu618) - LS-G98427

Source:

Human Cells

Tag:

His-Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

94.3 kDa

Price:

100 µg/$926

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