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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL6R / IL6 Receptor

interleukin 6 receptor

IL6R / IL6 Receptor is a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Gene Name: interleukin 6 receptor
Family/Subfamily: Interleukin
Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ
Target Sequences: NM_000565 NP_000556.1 P08887

Publications (2)

1
Interleukin 6 regulates psoriasiform inflammation-associated thrombosis. Wang Y, Golden JB, Fritz Y, Zhang X, Diaconu D, Camhi MI, Gao H, Dawes SM, Xing X, Ganesh SK, Gudjonsson JE, Simon DI, McCormick TS, Ward NL. JCI insight. 2016 1:e89384. (IHC-P; Human) [Full Text Article] [PubMed:27942589] [PMC:PMC5135273] Related Antibodies: LS-B6362.
2
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN Jr, Burns ME. Journal of neuroinflammation. 2017 14:121. (WB; Mouse) [Full Text Article] [PubMed:28645275] [PMC:PMC5481880] Related Antibodies: LS-C70920.

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Custom (8)
Sandwich (17)
Sandwich CLIA (2)
Target
IL6R / IL6 Receptor (27)
Reactivity
Human (9)
Mouse (6)
Rat (5)
Chicken (1)
Guinea pig (1)
Monkey (2)
Pig (1)
Porcine (1)
Rabbit (1)
Sample Type
Cell Culture Supernatants (4)
Cell Lysates (1)
Plasma (19)
Serum (19)
Tissue Homogenates (7)
Urine (3)
Publications
No (27)
Showing 1-25 of 27 results

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F264
Sandwich
96-Well Microplate
Mouse
6.144 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate  $540.00
LSBio image for ELISA Kit

Rat IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F24088
Sandwich
96-Well Microplate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Rat IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F4995
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $810.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F1001
Sandwich
12 x 8-Well Microstrips
Human
16 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1plate  $490.00
LSBio image for ELISA Kit

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F7705
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $780.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F5052
Sandwich
96-Well Strip Plate
Human
1.88 - 120 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates, Urine
1plate  $740.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F2676
Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1plate  $530.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F3364
Sandwich
96-Well Microplate
Human
4.096 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate  $470.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F11804
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $650.00
LSBio image for ELISA Kit

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F23549
Sandwich
96-Well Microplate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F23414
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Mouse IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F18587
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1plate  $650.00
LSBio image for ELISA Kit

Rat IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F18588
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1plate  $650.00
LSBio image for ELISA Kit

Pig IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F18589
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (CLIA) - LS-F29222
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Rat IL6R / IL6 Receptor ELISA Kit (CLIA) - LS-F37731
Sandwich CLIA
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F40366
Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Chicken IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F45152
Custom
96-Well Strip Plate
Chicken
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Guinea pig IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F45153
Custom
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Monkey IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F45154
Custom
96-Well Strip Plate
Monkey
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Porcine IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F45155
Custom
96-Well Strip Plate
Porcine
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Rabbit IL6R / IL6 Receptor ELISA Kit (Custom ELISA) - LS-F45156
Custom
96-Well Strip Plate
Rabbit
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F56541
Sandwich
96-Well Strip Plate
Mouse
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $550.00
LSBio image for ELISA Kit

Monkey IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F32129
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $555.00
LSBio image for ELISA Kit

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F37262
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit
Showing 1-25 of 27 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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