IL5

interleukin 5 (colony-stimulating factor, eosinophil)

IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

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Products

Proteins (34)

Type

Over-Expression Lysate (2)

Recombinant (32)

Target

IL5 (34)

Publications

No (34)

Tag

6His, C-terminus (3)

6His, N-terminus (2)

AVI-6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-GST (1)

His-T7 (2)

Mouse IgG Fc, C-terminus (1)

Myc-DDK (Flag) (2)

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Species

Dog (1)

Human (17)

Mouse (6)

Pig (3)

Rat (5)

Rhesus monkey (1)

Source

293F Cells (1)

293T Cells (1)

CHO Cells (3)

E. coli (18)

HEK 293 Cells (1)

Human (2)

Human Cells (1)

Insect Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (2)

Yeast (1)

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Purification

Purified (14)

Low Endotoxin Level

Low endotoxin level (20)

Biologically Active

Biologically active (17)

Animal-free

Animal-free (1)

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Rhesus monkey IL5 Protein (Recombinant) (aa20-134) - LS-G5851

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

26.1 kDa

Price:

10 µg/$388; 500 µg/$2,095; 100 µg/$1,116

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Human IL5 Protein (Recombinant GST, N-terminus) (aa20-134) - LS-G58974

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Pig IL5 Protein (Recombinant 6His, N-terminus) (aa22-134) - LS-G57353

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Pig IL5 Protein (Recombinant 6His, N-terminus) (aa22-134) - LS-G56913

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human IL5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76917

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.24 kDa

Price:

20 µg/$150

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Pig IL5 Protein (Recombinant His) (aa20-134) - LS-G23889

Source:

E. coli

Tag:

His

Molecular Weight:

16.9 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Rat IL5 Protein (Recombinant His-GST) (aa20-134) - LS-G23890

Source:

E. coli

Tag:

His-GST

Molecular Weight:

43.1 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Dog IL5 Protein (Recombinant His-T7) (aa20-134) - LS-G23888

Source:

E. coli

Tag:

His-T7

Molecular Weight:

17.0 kDa

Price:

10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430

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Human IL5 Protein (Recombinant GST) (Full Length) - LS-G29032

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL5 Protein (Recombinant) - LS-G27066

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

~29-35 kDa (SDS-PAGE)

Price:

50 µg/$402; 10 µg/$296; 1 mg/$1,933

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Rat IL5 Protein (Recombinant) - LS-G27188

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

13~21 kDa (SDS-PAGE)

Price:

50 µg/$478; 10 µg/$296; 1 mg/$2,653

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Mouse IL5 Protein (Recombinant) - LS-G27077

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

25-40 kDa (SDS-PAGE)

Price:

50 µg/$402; 10 µg/$296; 1 mg/$1,933

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Mouse IL5 Protein (Recombinant) - LS-G27081

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

26.2 kDa (SDS-PAGE)

Price:

500 µg/$1,058; 50 µg/$402; 10 µg/$296

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Human IL5 Protein (Recombinant) - LS-G27090

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

26.5 kDa (SDS-PAGE)

Price:

50 µg/$402; 10 µg/$296; 1 mg/$1,933

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Rat IL5 Protein (Recombinant) - LS-G27167

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

26.0 kDa (SDS-PAGE)

Price:

50 µg/$478; 10 µg/$296; 1 mg/$2,653

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Human IL5 Protein (Recombinant 6His, C-terminus) (Ile20-Ser134) - LS-G39925

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.2kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Human IL5 Protein (Recombinant) - LS-G137464

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 0.1 ng/µg of protein.

Price:

2 µg/$306

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Mouse IL5 Protein (Recombinant) - LS-G137646

Source:

Insect Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 113 amino acid recombinant protein has a predicted molecular mass of approximately 13.1 kD. The DTT-reduced protein migrates between 13 to 20 kD and the non-reduced protein at approximately 40 kD by SDS-PAGE. The N-terminal amino acid is Met.

Price:

10 µg/$299; 25 µg/$355; 100 µg/$720; 500 µg/$1,727

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Human IL5 Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G137385

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.2 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,095; 500 µg/$1,987

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Human IL5 Protein (Recombinant 6His, C-terminus) (Ile20-Ser134) - LS-G140240

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.2 kDa

Price:

10 µg/$317; 50 µg/$524

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IL5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122941

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.24 kDa

Price:

100 µg/$494

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Human IL5 Protein (Recombinant) - LS-G136251

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Molecular Weight:

26.5 kDa

Price:

10 µg/$370; 2 µg/$282

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Rat IL5 Protein (Recombinant) - LS-G131578

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~13 kDa

Price:

10 µg/$432; 1 mg/$8,695

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Mouse IL5 Protein (Recombinant) - LS-G131549

Source:

Insect Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

25 µg/$432

Select

Human IL5 Protein (Recombinant His, N-Terminal) (IIe20-Ser134) - LS-G132886

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

20kDa

Price:

10 µg/$289; 50 µg/$492; 200 µg/$982; 100 µg/$785; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309

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